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Characterisation of FIsh NEural STem cells in the midbrain – FINEST
There are fundamental questions in the field of neural stem cells (NSCs) biology: how do NSCs keep their multipotent and semi-quiescent state? How NSCs are recruited in healthy or pathological conditions? To tackle these questions, we propose to use fish models, whose brains have the peculiarity to grow continuously during whole adult life.
Characterization of sperm metabolic pathways and consequences of their deficiencies in humans: from male infertility to metabolic disorders. – SPERMetabo
relative to somatic cells, sperm cells require exceptionally high amounts of ATP; moreover, they must adapt
Charge transfer control in small molecular architectures – CHACRA
The CHACRA project aims to fundamentally study charge transfer (CT) processes in molecular assemblies adsorbed on a silicon surface functionalized with an insulating layer. Our work on manipulating and electronically decoupling individual molecules enables us to use low-temperature (9 K) scanning tunneling microscopy to induce, analyze, and control CT in carefully selected molecular assemblies.
Chemical genetics tools for investigating DNA junctions – InJUNCTION
prevalence of TWJs in our genome, with the notable exception of a study that was very recently published (2021)
Chemical stimulation of the innate immune response with ChX710: Toward a new class of antiviral molecules – ChemInnate
Viral infections are a major public health problem while our therapeutic arsenal remains very limited and relies mainly on a few direct acting molecules that act on the virus replication machinery. As part of the ChemInnate project, we are exploring another therapeutic approach: broad-spectrum antivirals that, instead of targeting the virus itself, block viral growth by modulating cell defense mechanisms.
Chemical valorisation of Lignins: toward fine chemicals and polymers – CHEMLIVAL
aromatic pool, as expected from this project, runs except that linked to vanillin production (like in Borregaard
Chemically addressing high curvatures at the nanoscale to optimize light-matter interactions – CARICATURES
to enhance these interactions and render the exceptional properties of quantum systems (single photon
Chimeric helices with improved properties for inhibiting target protein-protein interactions – CHIMPP2I
degradation by circulating enzymes, and with few exceptions generally display poor capacity, if any, to enter
Chimiokines adhésives: structure moléculaire, imagerie cellulaire et outils thérapeutiques – Adhékines
chemotactic cytokines, CX3CL1 and CXCL16 are exceptions: they are also expressed in transmembrane form
Cinema in the Soviet Union at war, 1939-1949 – CINESOV
xCinema in the Soviet Union at war, 1939-1949
