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Multifunctional implantable probes based on conducting polymer devices – PolyProbe
opposed to an electrode, yields recordings with exceptionally high signal-to-noise ratio. In PolyProbe we [...] will allow the simultaneous recording from an exceptionally large number of neurons and, at the same time
Bisubstrate and prodrug approaches for the rational design of new DXR nhibitors: Novel antimicrobial and antitubercular drugs – ANTITUB
Today, almost all important microbial infections throughout the world, such as tuberculosis, malaria, nosocomial diseases, are becoming resistant to antibiotics. Antimicrobial multi-drug resistance has been called one of the world's most pressing public health problems. It is therefore urgent to find innovative targets for new antimicrobial drugs.
Hybrid organic inorganic liquid crystal materials containing luminescent transition metal clusters – CLUSTOMESOGEN
Hybrid organic inorganic liquid crystal materials containing luminescent transition metal clusters
Sea-ice Evolution in Arctic Summer – SEAS
last summer (2012) satellites have recorded an exceptional reduction of the Arctic sea-ice pack to an extent
How the balance of excitation and inhibition shapes orientation selectivity and center-surround interactions in superficial layers in area V1: a combined experimental and modeling project – BalaV1
The activity of neurons in the primary visual cortex (V1) displays a very high level of synaptic «noise«. But is it really «noise«? Theoretical studies indicated that the «noise« is the result of the strong interactions - excitatory and inhibitory – taking place between neurons. These interactions must be balanced (so-called «balanced« state) for maintaining the activity level in a reasonable range. Our aim is to study the role of this emerging noise in the genesis of the responses in area V1.
Neuroethology of monkey social behavior – NEMOS
shelter, resources, or mere entertainment. With the exception of forest-dwelling hermits, the human living space
AFTER the end: reassembly of marine communities during the Early Triassic recovery – AFTER
The core idea of this project comes from recent discoveries on the PT crisis and its recovery by our team. These significant advances markedly<br />contrast with the classic, world-wide “delayed recovery” scenario and its associated paradigms.Our main goal is thus to test the “delayed recovery” model at a local to regional (i.e. ecologically functional) scale, looking for the potential drivers that influenced patterns and processes of the biotic recovery.
Universally high throughput Mass spectrometry-Tag Quantification in biological matrices: Alternative to radiolabeling – MTaQ
Mesuring the concentration of organic compounds at trace level in complex media is a challenging issue encountered in various domains (health, pharmacy, toxicology, environment, chemistry, …). The projet aims to provide an innovative answer based on mass spectrometry associated with specific chemical tagging in order to specifically target the compound of interest with a high detection sensitivity (expected quantification level for sub-nanomolar concentrations).
Integrative analysis of gene families involved in aromatic terpene biosynthesis in grapevine – InteGrape
The grapevine genome contains a large number of genes involved in the biosynthesis of terpenes, which are compounds playing a major role in wine aromas. The project goal is to understand the impact of the diversity of these genes on the richness of grape and wine aromas.
Identification of Matrix Proteins Affecting Crystal Texture in chicken and guinea fowl eggshells – IMPACT
Better understand the mechanisms of birds eggshell formation. Identify and characterize the interactions between proteins and minerals in the avian reproductive tract, which allow the formation of a highly elaborated ultrastructure of the eggshell
