Search
Rational design of chemosensory compounds targeting smell, taste and emotion – chemosim
Rational design of chemosensory compounds targeting smells, tastes and emotions
Understanding a threshold in Human evolution at 450-350 ka through the roots of Neanderthal behavior. – NEANDROOTS
Around 450,000 years ago, in Europe (and Western Europe in particular) began a long temperate or interglacial period following a severe glacial event that reduced habitable areas and depopulated the north-western part of the continent. Occupations became more numerous, with changes in behaviour and technical innovations.
Domestication as a step towards reproductive isolation – DomIsol
Genetic exploitation of wild relatives in crop improvement is a key alternative strategy to the massive use of inputs, and promotes the sustainability of agroecosystems. It is however conditioned by cross compatibilities between wild and domesticated forms, and fertility of the resulting progenies. <br />The DOMISOL project aims at characterizing the extent and molecular nature of reproductive barriers between wild and domesticated forms, and at investigating the underlying evolutionary processes.
Dynamic assembly of aromatic oligoamide foldamers for stabilizing protein-protein interactions – FOLDynamic
Combining the self-assembly properties of aromatic oligoamide foldamers into double helices in water with their protein surface recognition properties via their proteinogenic side chains to ultimately stabilize heteromeric protein dimers.
Effect of non-nutritive sweeteners on vascular function: deciphering the role of the T1R sweet-taste receptors – SOSweet
Effect of non-nutritive sweeteners on vascular function: deciphering the role of the T1R sweet-taste receptors.
Dynamics of cortical morphology during childhood development – SulcalGRIDS
Dynamics of cortical morphology during childhood development
Geothermal resources of crustal-scale fault zones: exploring new systems for competitive geothermal power production – GERESFAULT
Crustal fault zones (CFZ) correspond to permeability anomalies of crustal rocks. Instead of looking for temperature anomalies and artificially enhance the rock permeability, this project is focused on anomalously high permeability zones, where deep hot fluids naturally rise up to the subsurface. With a multidisciplinary approach on the Pontgibaud CFZ (Massif Central), the understanding of this hydrothermal system will be applied to european CFZ.
Mitochondrial and protease dysfunction in progeroid Cockayne syndrome cells and during age-associated processes – CS_AGE
Understanding the molecular defects responsible for premature ageing diseases like Cockayne syndrome (CS), is critical to develop treatments, which are dramatically missing to date, and also elucidate physiological ageing. We identified an altered pathway that involves mitochondrial an metabolic dysfunction in cells from CS patients, and rescued these defects in these cells, by scavenging oxidative/nitrosative molecules, paving the path to therapeutic approaches for CS.
Unravelling the Mars’ atmosphere Main Mysteries (MCUBE) – MCUBE
Unravelling the Mars’atmosphere Main Mysteries
Biomechanical cost quantification for wheelchair accessible cities – CapaCITIES
Locomotion with a manual wheelchair overloads the upper-limbs of the manual wheelchair users to an important stress, which varies according to the environment. To assist users in selecting the paths that preserve their upper limbs, a cost reflecting the physical demand to which the user is submitted according to the possible paths must be attributed and compared to manual wheelchair users' individual capacities.
