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ALTER-TRACK – ALTERnative TRACKing
Positioning and fleet tracking systems are very extremely dependant on satellite networks to work, both for the position and its transmission.<br />The project aims at breaking those strong limitations by designing a comprehensive solution dependable, reliable and resilient for vehicule tracking.
Popular logics for digital culture – POPLOG
This project starts from the observation that we know little about the specificities of relation to internet in popular classes. There are many studies on the uses of digital technology, but they are primarily interested in innovative uses of urban, youth, and graduates. There are many researches on popular classes, but they did not question the transformations induced by the digititalization of culture and the development of electronic communication.
Cognition and tool-use economy. Insights from experimental, neuro- and comparative psychology – ECOTOOL
Tools offer an economy by allowing the user to reduce the various costs (e.g., time) required to accomplish a task. If we keep in mind that tool use is also a matter of behavioral economy, several questions arise. Does the human tool-use propensity reflect the human ability to excel to direct toward the most economical options? Does cumulative cultural evolution reflect the human ability to extract from tool behaviors performed by conspecifics the ones that are the most economical?
Excited States of BiO-relevant systems: towards ultrafast DYnamics with conformational Resolution – ESBODYR
The experimental challenge consists in deploying novel experimental procedures (IR ns/ UV ns, IR ns/UV fs, helium droplets) in order to detect and identify bio-relevant systems from their IR spectroscopy. Then, the ultimate goal is to record a conformer-selective dynamics. The challenge for theoretical spectroscopy and dynamics of excited states of bio-relevant systems comes from the number of states of different nature which need to be described simultaneously in a balanced and accurate way.
Thioamide Activation for the Tuberculosis World – Tea-4-Two
In previous reports, we have shown that small molecule inhibitors of EthR stimulate the transcription of the ethA gene, which improves the bio-activation of ETH and consequently boosts its antibiotic activity, both in vitro and in vivo. However, as expected, these molecules were unable to boost the bio-activation of ETH in strains harboring mutations in ethA. Tea-4-Two is based on the discovery of a new generation of drug molecules that main circumvent the problem of drug resistance to ETH.
Role of Zbtb24 and DNA methylation in late B-cell differention and humoral memory – METHYL-MEMORY
Life-long protection by the humoral immune system is supported by long-lived plasma cells, which constitutively secrete antibodies, and memory B cells, which remain quiescent in the absence of the cognate antigen. As both cell types are affected in patients suffering from the ICF syndrome, the elucidation of the link between the genetic basis of this disease and the immunodeficiency should bring new light on the physiology of these cells and help find new treatments for this disease.
Genesis and maintenance of bacterial secondary chromosomes – MAGISBAC
The MAGISBAC project aims at providing both a global and detailed view of how secondary replicons adapt to their host and become domesticated in bacteria.
On the Government of Familial Feelings: Towards a Sociology of Contemporary Ethopolitics – ETHOPOL
ETHOPOL is a research program hosted by the University of Toulouse Jean Jaurès. Five social scientists collaborate to analyze the diversity of family regulations and their subjective consequences. Members of this team work on adoption, medically assisted reproduction, surrogacy, paternity testing, and the regulation of birth; they aim to study how institutions frame families and modify the way subjects feel, think, and act.
Rebuilding after an earthquake: ancient experiences and innovations in Pompeii – RECAP
Faced with recurrent risks, did Roman builders develop earthquake-resistant construction techniques? An international initiative, RECAP project follows a multi-disciplinary approach, calling upon the archaeology of construction, sociology, IT, structural engineering and geology, in order to determine the practicalities of reconstruction and the technological choices adopted..
Crystallisation of seeded Silicon, impact of Light Impurities and Defects – CrySaLID
Answer to the challenge of the control of the final crystalline structure (growth from seeds, orientation selection, and parasitic grains) of the defects and of light impurities: multi-scale experiments and simulations.