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Unraveling the dynamics of hippocampal-cortical interactions during the formation of recent and remote memories: behavioral, cellular, molecular and functional bases – MemoryTrack
Decrypting the dynamics of neuronal and vascular interactions within the hippocampal-cortical interface during memory formation and stabilization, two processes which are altered in neurodegenerative diseases
Global surveillance of infectious agents: molecular typing kits and databases – MicroType
Constitution of genetic identification profiles and associated databases is essential for the surveillance of infectious agents that represent a natural, accidental or provoked biohazard. During the p
Topological properties of periodically driven dynamical quantum systems – TopoDyn
The development of theoretical tools allowing the highlight of exotic topological properties that are specific to dynamical systems is a necessary step to handle the complexity and the universality of various phenomena.
Experimental and theoretical study of the detonation of granular explosives – ATOLE
The ATOLE project aims at studying the underlying mechanisms involved in the detonation of oxygen-deficient explosives with granular structure. These still barely understood processes produce large
Characterization by Cryogenic Electron Microscopy of Structural Differences in Protein Translation between Eukaryotic Pathogens and Mammals – CryoEM80S
The relative conservation of the ribosome among eukaryotes complicates substantially the search for specific drugs against eukaryotic pathogens such as certain protozoa like plasmodium and kinetoplastids.<br />Our work along with other studies demonstrates the existence of significant structural differences between ribosomes of protozoa and mammals. Using Cryogenic electron microscopy, we endeavor to investigate such structural differences.
Targeted delivery of therapeutic siRNA to Ewing sarcoma junction oncogene by traceable diamond nanocrystal – antibody fragment conjugate – DiamESTar
The main objective of DIAMESTAR project is to evaluate the efficacy of a new small interfering RNA(siRNA)/nanocarrier complex to treat Ewing sarcoma (ES) metastatic tumor xenografted on mice, when thi
AGuIX® theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of brain tumors – PhotoBrain
Photodynamic therapy (PDT) for brain tumors appears to be complementary to conventional treatments. Numerous studies show the major role of the vascular effect in PDT tumor eradication. For interstiti
PAN-ARTIC OPTIONS: HOLISTIC INTEGRATION FOR ARCTIC COASTAL-MARINE SUSTAINABILITY – PAN-ARCTIC OPTIONS
The Arctic Ocean is experiencing an environmental state-change with expanding human activities ranging from commercial shipping and energy development to ship-based tourism. Accordingly, with involve
ARCTIC climate change and its impact on Environment, infrastructures and Resource Availability – Arctic-ERA
ARCTIC-ERA will address critical aspects of human well-being and sustainable use of Arctic infrastructure and resources under the conditions of regionally accelerating global warming. The ongoing and
Designing an improved network of long-term monitoring sites for arctic vertebrates: towards a better involvement of local communities through participatory science programmes – TAMANI
The arctic environment is changing at an alarming rate and it is essential to understand the consequences of such changes on arctic biodiversity. Longterm monitoring programmes of key arctic species a