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Speech-in-noise Intelligibility Deficits: Designing Psychophysical and Electrophysiological Markers of Spectral Shape-Coding Sensitive to Cochlear Synaptopathy – INSPECTSYN
At present, it is estimated that over 10% of individuals with clinically-normal audiograms have significant difficulty understanding speech-in-noise (SPiN). In particular, synaptopathy - the loss of s
Multimodel Streaming Data Management – POLYFLOW
The need for addressing data variety paved the road to the advent of multidatabases, which the Turing Award winner M. Stonebraker endorsed. Multi-databases include multistores, which expose a unified
Investigating the digestive microbiota of detritivores as a bioreactor of leaf litter decomposition in freshwater ecosystems – DIET
The process of plant litter decomposition is central in the global carbon cycling, and this process is substantially supported by freshwater ecosystems. Headwater streams receive massive inputs of aut
RNA condensation and translation regulation upon physiological aging – POSTRAGING
Systems-wide analyses performed over the last 10 years have shown that a restricted number of genes undergo significant changes in expression upon aging. While recent comparative multi-omics studies h
Determining the role of SLC6A4 polymorphisms on the anti-depressant response: from causality to identification of molecular signatures and robust biomarkers – PolyDep
Major depressive disorder (MDD) is a complex multifactorial disorder. More than half of the patients show no clinical improvement in response to first-line antidepressants (ADs). Understanding of thes
Pioneering the Activation of Distal Regulatory Elements during the EMT – PADRE
Distal regulatory elements, such as enhancers, are critical determinants of development and disease through their role in the spatio-temporal control of gene expression. The cell-type-specific activat
Uncovering the mechanisms & dynamics of proximity-dependent interallelic interactions – InterAlleles
The control of gene expression relies on cis-regulatory sequences. In many cases, however, proper regulation also requires interactions between homologous alleles. The mechanisms underlying this form
Probiotics and Phytonutrients for the Health of the Gut-Brain Axis – ProPhySICe Lab
The gut-brain axis in Alzheimer's disease. A neurodegenerative disease is a generic term for a heterogeneous group of pathologies affecting various populations of neurons in the central nervous system
Plankton biodiversity through remote sensing and omics in the Mediterranean Sea – PETRI-MED
The objective of PETRI-MED is to develop novel strategies to determine and monitor the status and trends of microbial plankton biodiversity in the entire Mediterranean Sea, supporting the assessment o