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Activation Mechanism of Bora-Plk1 Regulating Entry into mitosis – AMBRE
Decoding the molecular mechanism leading to mitotic entry
Characterization of a novel DNA binding domain in BRCA2 protein – FUNBRCA2
BRCA2 tumour-suppressor protein is well known for its role in DNA repair by homologous recombination (HR). It facilitates the loading of RAD51 recombinase at DNA double-strand breaks. This function is
Nanosensor for the size-discrimination and purity analysis of peptides – PurPepSize
The aim of our project is to develop an innovative and low-cost nanosensor using nanopore technology for the single-molecule size-discrimination of peptides with a single amino acid resolution, which
Identification of host and parasite causative and remedial factors of neuroinflammation in the context of cerebral malaria – NEUROCM
In most tropical areas where malaria is endemic, young children are most prone to develop severe malaria, and eventually to die. Despite a recent decrease in malaria mortality due to extensive malaria
Production of recombinant membrane proteins embedded in heterologous caveolae membrane – CAVEOTANK
Membrane proteins (MPs) play crucial roles in a wide variety of cellular processes. They are involved in numerous pathologies and are thus important drug targets. Their overexpression in heterologous
Hierarchical Self-Assembly of BioMaterials – SELFBIOMAT
The production of custom-made functional biomaterials using sustainable synthetic processes is an important challenge for modern society. Nature provides inspiring examples of biomaterials which are s
Precision Measurements of Electroweak Parameters – PMEP
The discovery of the Higgs boson during the LHC Run 1 completes the experimental validation of the Standard Model (SM) of high-energy particle physics. Its particle spectrum is fully established, and
Linking microevolutionary and macroevolutionary processes in freshwater mollusks from the East African Rift. – EVOLINK
Modern evolutionary theory developed with the main objective to explain and predict changes in populations from one generation to the next, and how species evolve. Largely independently, paleontologis
Characterization of pre-EJC factors and their role in cell fate determination – spEJCificity
The Exon-Junction Complex (EJC) plays a central role in post-transcriptional gene expression control. This multiprotein complex deposited onto mRNAs, participates to major steps in the mRNA life-cycle
Energy transition, territories, hydrogen ans society – TETHYS
The TETHYS research project is part of the field of technical democracy and proposes to answer, in close collaboration with the actors of the territory, a set of questions related to the process of energy transition related to hydrogen, from the follow-up Demonstrators for the «putting into democratization« of issues that are both general and very practical, aims to go beyond the traditional approaches formulated in terms of social acceptability of risks.