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New neuroprotective and neuroregenerative compounds for Parkinson`s disease – ANTIPARK
Around 150.000 people in France are affected by Parkinson’s disease (PD) and 10.000 new cases are diagnosed every year. This is the 2nd motor handicap after cerebral vascular breakdown. PD is characte
Thermally Assisted Mechanical Dewatering – DMAT
Sustainable development requires the use of renewables as alternative feedstocks for fuel, chemical and material productions. Currently, share of renewable raw materials runs at best to a few percents
Singlet oxygen: from damage to proteins to the development of biosensors and generators – SOxygen
Oxygen is a reactive species, whose reactivity can be increased by light irradiation of certain molecules (photosensitization). This phenomenon is still not well characterized at a molecular level, especially for some of the biomolecules that are essential to life, proteins. We propose to increase our knowledge on this topic.
Phosphorus-containing dendrimers: innovating molecules for the treatment of Rheumatoid Arthritis – INNO-THER-RA
Our project aims at proposing a new therapy against Rheumatoid Arthritis (RA). RA is considered an auto-immune and inflammatory disease affecting 0.5% of the population in developed countries (300,000
Redox-active 1,4-naphthoquinones to kill malarial and schistosomal parasites – SCHISMAL
Our previous work led to the selection of potent antimalarial 2-benzyl-3-methyl-1,4-naphthoquinones (benzylNQ) active against various multi-resistant strains of Plasmodium falciparum and in P. berghei
Mediator-less Glucose BioFuel Cell – M-GBFC
Glucose BioFuel Cells (GBFCs), whose redox reactions are catalyzed by enzymes, hold a strong place in worldwide research. Though their first targeted application was implantation inside animals, this
Endothelial Microparticles for Predicting Cardiovascular Risk – EMiRisk
Diseases of the heart and the cardiovascular system are the leading cause of mortality in France, accounting for > 180 000 deaths per year. Their incidence is expected to increase further in the next
Preparation and in vivo analysis of “mCD4-HS12”, a synthetic glyco-conjugate which inhibits HIV entry. – HEPACLAMP
Human immunodeficiency virus (HIV-1), the virus that causes AIDS has infected 60 million people (half of which has died) and remains one of the leading causes of death worldwide. The availability of s
Microplate assays and on-line analyzer for the spectrofluorimetric determination of carboxylic, thiol and amine compounds – CARBOTHIOLAMINE
The determination of volatile fatty acids (VFA), thiol compounds and amino compounds in environmental or biological samples require pre-treatment of samples (eg extraction) and expensive analytical te