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Food safety represents a global major issue. Human and animals are exposed to hundreds of potentially toxic substances, with possible cocktail effects representing a health risk that are hardly predictable. The Deoxynivalenol (DON) mycotoxin is among the most widespread food contaminants and represe

BARRIER is a proof of concept project with multidisciplinary expertise for demonstrating, from the laboratory to a pilot process, that selected bacteria can protect microalgae when growing in various waters including produced water, seawater or wastewaters containing toxic compounds, providing highe

The overall impact of mercury (Hg) pollution is indisputable (Minamata convention on Hg), and some populations are recognized as particularly vulnerable and at high risk. The Brazilian Amazon is one of the regions most affected by Hg in the world. In this area, Hg can be released into aquatic ecosys

Anthropogenic noise is still not considered a serious contaminant with an impact on human health. However, the prediction of the number of people who will be affected by hearing and non-hearing diseases in 2050 has been revised upwards by WHO: it has tripled in 3 years, from 700 million to 2.5 billi

Anthropogenic environmental changes are a real threat to pollination and the associated ecosystem service. Among these changes, the increase of atmospheric pollutants such as ozone (O3) remains understudied despite its probable impact on plant-pollinator interactions. In these interactions, host rec

Human populations are exposed to environmental mixtures (cocktails) of chemicals. Risk assessment of the potential adverse health effects of such real-life mixtures is one of the major challenges faced by scientists and regulators. Partners recently developed a new methodological approach to perform

Tracheotomy is procedure that involves introducing a tracheal tube through the neck, and then allows a patient to breathe without the use of upper airways (nose, mouth). It can be indicated in patient with respiratory distress due to a pulmonary infection by bacteria, parasites or respiratory viru

The objective of LUCIOLE is to characterize the impact of artificial light at night (ALAN) on coastal areas by answering the question Does the light pollution at night disrupt the biological timing of marine organisms living in coastal environments and what are the consequences? To answer to this is

The contamination of our resources by environmental pollutants, such as pesticide residues is a major public health issue. Although brain is not often studied in classical toxicological studies, its exposure to environmental pollutants during its development could have repercussions at key moments o

More than half of the world population is now living in cities. Few reports have addressed issues regarding the microbiological quality of urban surfaces and their potential role as vectors of bacterial pathogens. Here, we present an original PRME proposal exploring the functioning of urban surface

New technologies involved in communications, energy or medicine have increased the use of elements such as those belonging to the platinum group, lanthanides, indium (In) and germanium (Ge). However, their fate and toxicity to aquatic ecosystems are still poorly understood compared to the base metal

Freshwater pollution, especially by pesticides and pharmaceutical residues, raises growing concern for human and environmental health. Some chemical compounds are of great concern, due to their ubiquity and toxicity. Among them, imidacloprid, a neonicotinoid insecticide, and diclofenac, a nonsteroid

Exposure to agricultural pyrethroids during perinatal period is associated with an increased risk of autism spectrum disorder (ASD). Environmental agencies also alert on their extensive indoor use, including by pregnant women. We previously found that concentrations of household pyrethroids in indoo

Our interdisciplinary consortium aims at understanding the future evolution of the allergenic pollen grain in a context of increasing atmospheric CO2 concentration. Pollen will be collected from phleum pratense plants grown in the field under a CO2-enriched atmosphere and under drought stress. Timo

Besides anthropogenic pollutants, proliferations of phytoplanktonic cyanobacteria in freshwater ecosystems represent a source of growing concern worldwide due to the ecological and economical disturbances they create, as well as the significant impact of their toxins on animal and human health. One

Recent studies suggest that transgenerational metabolic impairments induced by endocrine disruptors (ED) exposure are key contributing factors in amphibian population decline by altering individual fitness. However, several questions remain to be explored: How do obesogenic EDs act in frogs? What ar

Omnipresence of glyphosate in food and water represents a significant public health concern and its toxicity in mammals is subject to many controversies. Glyphosate acts as an herbicide by inhibiting of a central enzymatic step of aromatic amino acid biosynthesis present in plants and in all microor

Bioplastics are nowadays considered as a sustainable alternative to conventional polymers, especially for specific applications such as in agriculture which requires eco-friendly materials and, preferably, biodegradable polymers. EcoBioPlast will contribute to understand and to model the biotic and

Ulcerative colitis (UC) is a chronic inflammatory bowel disease caused by genetic and environmental factors. The latter act firstly as neonatal primers: their exposure during the perinatal period disturbs early maturation of gut microbiota and immune system and induces an increased susceptibility to

Environmental contaminants contribute to the increased incidence of non-alcoholic fatty liver disease and reproductive disorders. The links between hepatic and reproductive disorders suggest etiological mechanisms that would involve the disruption of a bidirectional dialogue between liver and testis

In the context of the global plastic pollution crisis, IsotoplastX aims to provide a more comprehensive view of micro- and nano-plastics (MNPs) impact on human health. It focuses on their fate and behavior from the cell to the whole animal, comparing their respective size-dependent and chemical cont

Recently, important dark reactive oxygen species (ROS) production in littoral ecosystems has been discovered. The reported H2O2 concentrations, 1000 times higher than previously known natural concentrations, result from the O2 reduction by the Fe2+ stemmed from bacterial sulfatoreduction. The ESCIS