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Interest in the use of nanostructured materials in medicine and diagnostics has grown rapidly in recent years. The dimension of so-called nanomedicine results in new medical effects and requires novel, scientifically demanding chemistry. Thus, drug delivery systems with controllable size and shape i

Rapidly accumulating environmental sequencing data have revealed that eukaryotic microbes are far more diverse and complex than previously thought. However, meta-barcoding and meta-genomics surveys are severely limited by the fact that the majority of environmental sequences do not match a sequence

In presence of abrupt (financial crisis or epidemics) or long-term (environmental or demographic) changes, one needs to use dynamic tools, to detect such changes from observable data, and to re-estimate models and risk quantification parameters, based on a dynamic and long-term view. Classical decis

The project investigates the agency of artistic materials as a factor in cross-border Franco-German cultural networks. Specifically, this study focusses on the example of the exchange of the raw material alabaster and of alabaster artworks between France and Germany around ca. 1350-1650, i.e. during

The goal of the MULTIPROBE project is to develop a new methodology for the in situ and operando characterization of catalysts based on a unique combination of transmission electron microscopy and X-rays techniques, including 3D and environmental TEM, EELS spectroscopy, macro- and micro-scale X-ray a

Thanks to a collective and transversal analysis, the objective of FONDASCIENCE is to study the role of philanthropic foundations in the development of scientific research from 1910 to 1956, by exploiting archives that have been little questioned or even totally unpublished until now. The starting hy

During the past thirty years chemists have designed, constructed and investigated a large variety of molecular devices and machines by exploiting photonic, electronic and chemical inputs. Such molecular machines hold great promise for major progress in multiple domains and the field has been recogni

Our Solar System is the only planetary system that can be thoroughly explored by spacecrafts and by the analysis of planetary samples in the laboratory. It provides a unique glance at the mechanisms leading to stars and planets formation, a vision that is complementary to that derived from remote ob

The PV sector is experiencing a fast growth and is becoming one of the main pillars for the energy transition. The goal of 30% efficiency (challenging roadmap issued during COP21, initiated by IPVF and named “30-30-30”) will be extremely difficult to reach with classical solar cells based on single

The fluorine element is used in domains as diverse as medicine, energy, microelectronics and everyday plastic objects. Rare in the natural state, a tremendous number of elegant syntheses of fluorinated organic compounds has been developed by using catalysts to improve both activity and selectivity.

Among all the renewable energy sources, solar energy is the most powerful source far ahead wind or geothermal energies. The possibility of an efficient and low-cost direct conversion of the sunlight energy into electricity is a clear scientific and technological stakes. Dye-sensitized solar cell (DS

By 2021, cloud IP traffic will be the most part of an Internet traffic that complexifies with an increasing devices diversity and traffic dynamicity. A proposal framed at the cloud to face this situation is the Knowledge Defined Networking (KDN), where Machine Learning (ML) and Artificial Intelligen

By 2021, cloud IP traffic will be the most part of an Internet traffic that complexifies with an increasing devices diversity and traffic dynamicity. A proposal framed at the cloud to face this situation is the Knowledge Defined Networking (KDN), where Machine Learning (ML) and Artificial Intelligen

The societal benefits of opening up public data are expected to be huge. This is particularly true with Public Procurement Data which are supposed to help discover and dismantle corrupt activities by facilitating critical information, tools, and mechanism for judicial enforcement. In a multidiscipli

MultiPhos project aims re-engaging with Solid State Chemistry approach. Its main goal is the search of multiferroics solids based on polyanionic frameworks investigating a synergy between non-centrosymmetric proper and magnetically-induced improper ferroelectricity. Partners from 4 institutes and di

MALCOM-X aims at elucidating allelopathic compounds from the moss Physcomitrium patens. These compounds are used by the plant to control both its interaction with neighbours and its own development. In particular, two types of compounds will be searched, based on their signalling roles in strigolact

The project offers a new interpretation of the societies of Ukraine and Moldova which seem to have settled into a lasting state of political and social instability at the very doors of the European Union. The originality of the project lies in looking at these societies not as peripheral versions of

Among all the renewable energy sources, solar energy is the most powerful source far ahead wind or geothermal energies. The possibility of an efficient and low-cost direct conversion of the sunlight energy into electricity is a clear scientific and technological stakes. Dye-sensitized solar cell (DS

For a few years, we have observed the rise of new collaborative work spaces (NCWSs) remote from major cities. These places of social interaction echo the expectations of a population looking to evolve at the fringe, both geographically (away from great urban centers) and socially speaking (hoping fo

The PV sector is experiencing a fast growth and is becoming one of the main pillars for the energy transition. The goal of 30% efficiency (challenging roadmap issued during COP21, initiated by IPVF and named “30-30-30”) will be extremely difficult to reach with classical solar cells based on single

ANABASE aims at sharing the complementary expertise of three academical partners (CEA-IRIG, CNRS-Néel,INL) to realize innovative AlN nanowire-based LEDs for deep UV emission. CEA-IRIG is at the cutting edge of the international research effort on NWs. Néel partner has a recognized expertise in elect

The TESMARAC joint laboratory focuses on the development of selective supports necessary for the separation and determination of radionuclides at trace level in complex matrices in order to meet demands related to the management of (TE)NORM ("(Technology-Enhanced) Naturally-Occuring Radioactive Mate

Aquaculture is an important source for food, nutrition, income and livelihoods for millions of people around the globe. Intensive fish farming is often associated with pathogen outbreaks and therefore high amounts of veterinary drugs are used worldwide. As in many other environments, mostly applicat

Eukaryotic genomes are mainly composed of repeated sequences including transposable elements (TEs), highly mutagenic mobile DNA sequences which constitute a serious threat for the genome integrity. These TEs reside in the genome of all species and represent almost half of the human genome. A fine co

Forest canopies buffer climate extremes in the understory. This buffering capacity is key to explain understory biodiversity and forest regeneration, and thus forest resilience to climate change. It is also important for recreational activities. Forest management practices impact these ecosystem ser

While insecticides are essential tools in agriculture, their effects on ecosystems are deleterious. One third of insecticides (e.g. neonicotinoids, fipronil and broflanilide) act by targeting insect pentameric ligand-gated ion channels. The project aims to understand the molecular mode of action of

DELTA Project Description Project Background Deltas are dynamic systems driven by constantly changing interactions between land-based fluvial and ocean processes. These flat agricultural lands, accounting for less than 1% of Earth’s land, are vital for the food security of more than half a bill

The project seeks to produce a tool for assisted interpretation of artistic images. Taking the form of a prototype adapted for three museum settings (Museum of Fine Arts of Lyon, Lille Palace of Fine Arts and the MNHA of Luxemburg), the device will allow the study of the different levels of organiza

Most living cells exhibit a difference in electrical potential across their plasma membrane resulting from differences in ion concentration maintained by ion channels and pumps. The membrane of a neuron can be suddenly (˜1 ms) depolarised (its intracellular potential rising from -70 mV to +30 mV) by

The major transitions of the 21st century, notably digital and environmental, are revolutionizing our lifestyles and have ultimately transformed the modes of industrial production. In addition, companies no longer define themselves solely by what they do, but also by their approach. Thus, innovation

Epoxy resins used in Building and Civil Engineering are submitted to thermo-oxidative, humid and structural relaxation ageing. The lack of reliable methods for lifetime prediction adapted to those complex in use conditions limits at the moment their use in highly requiring industrial sectors (nuclea

Neurons and neuroendocrine cells release neurotransmitters, neuropeptides and hormones through calcium-regulated exocytosis. The ultimate step of exocytosis involves fusion of secretory vesicles with the plasma membrane, leading to the merging of these two compartments. Following exocytosis, the exc

The project CRISIS is conceived to to give rigorous mathematical grounds to the description of heterogeneity effects, singular behaviours and multi-scale processes which occur and interplay in several real world phenomena related to fluid mechanics, and improve their theoretical understanding. We ha

Over a large part of Antarctica, the surface mass balance (SMB) is controlled by a few extreme events, resulting in a high natural variability of this parameter. In particular, extreme moisture intrusions linked to Southern Ocean Atmospheric Rivers (ARs) have been recently demonstrated to be major s

The aim of the CUPID-1 project is the development of a complete bolometric detector system capable of investigating neutrinoless double beta decay – 2b0n- with unprecedented sensitivity. The project will be dedicated to the design of a detector tower capable to be operated in a next generation 2b0

Exposure to toxic gases or volatile organic compounds (VOCs) affects safety and public health. More than 6.5 million deaths per year worldwide are attributed to environmental pollution (indoor and outdoor air quality). With the Internet of Things, large-scale deployment of gas sensors becomes access

Regenerative therapy based on the use of mesenchymal stem cells (MSC) is a promising approach for the treatment of stroke. The beneficial effects of MSC appears to be mainly related to the secretion of cellular factors and/or extracellular vesicles (EV). Heparan sulfates present on the surface of pr

The project Religious Dissidence and Reception of the Reformation in the Renaissance in Spain (16th century) (henceforth D4R) has a double objective in Digital Humanities: on the one hand, the processing of a corpus of 16th century documents on the Reformation in Spain and, on the other, the develop

Business intelligence (BI) technologies such as data warehousing and On-Line Analysis Processing (OLAP) are major decision-support tools that used to necessitate heavy financial and human investment. Yet, there now exist numerous free BI suites including proprietary, open source and/or cloud solutio

Auditory hallucinations (AH) are among the most frequent and disturbing experiences described by individuals with psychosis and other mental and neurological disorders. AH are also present in the general population. The adoption of a symptom-focused approach has led to significant improvements to t

Fluids, lithology and structure are known to play a major role in shallow fault slip modes but there is a major issue: Does one of them take precedence over the other two or are they linked? Are really fluids a key parameter? In recent years, studies in Japan, Costa Rica or New Zealand try to find t

Positron sources are essential to the future e+e-/µ+µ- collider projects (ILC, CLIC, FCC-ee, LEMMA, etc.) with challenging critical requirements of high-beam intensity and low emittance necessary to achieve high luminosity. The intensities required from the positron sources at the future colliders a

The RefWar project focuses on the protection in France of "war refugees", i.e. those who are forced into exile as a result of armed conflict in their country of nationality or residence. It aims to shed light on a major dimension of contemporary forced migration by assessing the applicable legal ins

Efficient coupling between electronic and biological systems requires an interface for converting electronic signals into ionic (or chemical) signals, and vice versa, ideally with high sensitivity and speed. Unfortunately, the performances and functionalities of present electro-ionic devices poorly

Transposable elements (TEs) constitute a large portion of eukaryotic genomes. Because of their mobility, they are potential threats for the host genome. One big challenge in biology is to determine how the chromatin silencing machinery establishes and maintains TE silencing. Based on preliminary dat

The magnitude of ecological crises and environmental degradation puts public policies in the face of a double requirement of efficiency and justice. In this project, we aim to contribute to this challenge from the angle of environmental justice, a recent issue in both academic literature and public

Marine environments undergo rapid changes under the influence of various pressures (human footprint, climate change) and the monitoring of their ecosystem status becomes critical. Such a monitoring requires gathering data, to process them and to extract indicators summarizing the status of the envir

As stated in the National Strategy for Research report (SNR, Action Plan 2017, ANR Call), while presenting one of the five priorities of Challenge 3 "Industrial Renewal" (Orientation 14 "Design of new materials"): "The future industry will rely, in part, on multi-functional materials and on i

This project aims at providing supplementary knowledge on stuttering, in order to help with its diagnostic and speech therapies. The project involves a multidisciplinary team including researchers in linguistics, computer science and neurology on the one hand, and, on the other hand, speech-language

The cerebellum is a brain structure well-known for its role in the control of motor function. Yet, a growing body of clinical as well as experimental data point to its implication in cognitive functions. The cerebellum display a peculiar anatomical organisation, subdivided in 10 distinct lobules tha

While it is well known that the drying of latex films play a critical role in paints, cosmetics and inks, a realistic description of the drying process is in fact not yet available. The final properties of the film, such as its adhesion, its optical and mechanical properties depend not only on the f

The overarching objective of HILIAISE is to better understand and model the human imprint on semi-arid energy and water cycles. To obtain this objective: 1) The project will have a long term field campaign with a 15-day Special Observing Period during summer 2020 over the Ebro basin in northeast

This study represents a novel and efficient approach for the treatment inflammatory pain, characterized by the design of squalene-based nanomedicines allowing the specific delivery of Leu-Enkephalin (LENK) neuropeptide into inflamed tissues after intravenous administration. The research project is a

The project addresses the study of mesophases constituted of molecules, hereafter called "carbo-mesogens", built around a C18 carbo-benzene core. This new type of core includes the following features: all-carbon composition, hexagonal symmetry, extended flatness, high magnetic aromaticity, "acetylen

Chirality generally refers to molecules, objects, or materials which can coexist in two non-superimposable forms, called enantiomers, showing mirror image relationship, and is therefore present in many scientific areas related to chemistry, biology, astronomy and physics. Although chiral materials i

This research proposal aims at providing exhaustive evidence and theoretical insights on the effects of globalization shocks on the workforce composition of EU firms and local labor markets. The final objective is shedding light on a new channel through which globalization can affect the welfare of

HERMES wants to take high-speed atomic force spectroscopy and microscopy (AFM) to the next level, opening a new experimental window in molecular biophysics experiments. We will develop nanosecond atomic force tracking in liquids and ultra-high-speed force imaging, with a spatial and force resolution

COSMHIC is a fundamental research project, which aims at exploring how dynamical processes drive star formation and its galactic-scale properties. It will timely strengthen the leadership and synergy the IPAG Grenoble, DAp Paris-Saclay, and LPENS Paris groups have developed over the years, in the fr

Inflammation is the resulting cellular and tissue response to an aggression, whether due to an infection (bacterial or viral), an injury, an auto-immune disease, or a yet unidentified agent (Behçet’s disease). Blood vessels are in first line when an inflammatory process is triggered because they are

Our body is constantly processing a wide range of sensory information that enables us to interact with our environment. Among these, somatosensory information is involved in many crucial functions, ranging from detection of potentially harmful stimuli to social interactions within a group. Somatosen

Globalisation, technological change and demographic changes are currently altering altogether the face of the labour market in most developed countries. New and, in particular, digital technologies as well as new markets create job opportunities. But these opportunities are not evenly spread across

Forest canopies buffer climate extremes in the understory. This buffering capacity is key to explain understory biodiversity and forest regeneration, and thus forest resilience to climate change. It is also important for recreational activities. Forest management practices impact these ecosystem ser

Owing to a high-resolution cathodoluminescence systematic study of carbonaceous chondrites and NASA OSIRIS-REx returned samples, O-Return is a 4 years ANR project aiming at gaining new information on the conditions of formation (e.g. condensation, crystallization, annealing) of refractory inclusions

Biological invasions are defined as the successful establishment of species outside their native range. They are a component of global change and induce substantial impact on invaded communities and ecosystems as well as considerable economic loss. While the ecological effects of invasions are well

The DINLANG project aims to capture how semiotic resources (speech/sign, gestures, actions) are coordinated to construct meaning through the language practices transmitted to and used by children during French family dinners. Ethnographic methods will be used by four teams to collect dinners in two

Nanoobjects are more and more subject of interest in academic and industrial research. However, most of the studies essentially focalize on the properties of individual objects. Indeed, a key challenge to study collective properties – opening doors to new applications – is the organization of such o

By producing protein-rich seeds without N-fertilizers, legumes can contribute to satisfying the growing demand for plant proteins for human and animal nutrition while reducing environmental impacts. PEAVALUE will target pea (Pisum sativum L.), one of the most important grain legume crops in Europe,

The ETIC project (effects of digital images on consumers) aims to study the negative influences of digital advertising and promotional images on people. Individuals are analyzed in their double hypostasis, as consumers of images on screens and of distributors of images on social media. The objective

The obesity epidemic continues unabated and currently available pharmacological treatments are not sufficiently effective. The consistent worldwide disparity in prevalence of severe obesity strongly suggests that biological factors, i.e. physiological sex differences, in particular sex hormones cont