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FLT3 inhibitors for the treatment of neuropathic pain – NEUROPATH
Neuropathic pain (NP) is a chronic pain disorder caused by nerve damage secondary to other pathologies (eg diabetes), or surgical or traumatic lesions. Treatments for NP are non-specific, inefficient and generate side effects. NEUROPATH researchers found that NP was selectively initiated and maintained by stimulation of the Tyrosine Kinase Receptor FLT3, which therefore appears to be a relevant therapeutic target for NP.
Mitotic memory of active transcription in mouse ES cells – MitMAT
impair self-renewal. Hence, ES cells constitute an exception regarding the general mechanism of epigenetic
Methylene resonances: invaluable probes for the study of proteins – CH2PROBE
the amino acids contain 2H, 12C and 15N nuclei, except for the glycine residues. Since they are responsible
Design of polyvalent organic electron donors: Applications in organic and polymer synthesis – iPOD
agents with neutral organic structures and exceptionally negative redox potentials have received a renewed
Elucidating the in vivo mechanism(s) of peroxiredoxins in oxidative stress protection and aging – PrxAGE
similarly other Prxs have multiple phenotypes, but except the two above examples, unambiguously linking them
Small HSPs Inhibitors to Treat Idiopathic Pulmonary Fibrosis – SHOT-IPF
Smad4 is a key TGF-ß1 signal transducer protein Except for pirfenidone and nintedanib that slightly reduce
From Advertisment to marketing. Pharmaceutical enterprises, patients, physicians and the construction of medical markets – GEPHAMA
corporations, physicians and the construction of pharmaceutical markets.
Impact of DNA methylation on meiotic recombination in Arabidopsis thaliana – MeioMeth
Factors that control the position and the rates of meiotic recombination events are poorly understood but suggest the presence in various species of an underlying epigenetic control. We are going to test if DNa methylation is involved in this control.
Gas microbubbles decorated with gold or magnetite nanoparticles: composite objects for multi-scale investigation of magnetic, magneto-optical and optical responses. – AirDeco
self-assembly) is given by the obtaining of exceptionally stable MBs using one of the fluorinated phosphates
Design and development of a tunable EUV source for the characterization of multilayer mirrors (Tunable Parametric Laboratory UV Source) – TPLUS
Except the synchrotron radiation or the free electron laser, which are only available in large facilities
