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Knowledge integration under time constraint – KINETIC
We study project teams, and aim at finding what drive their capacity to develop radical innovation in conditions of extremely tight resources and time. We combine real-world data from big companies (case studies) with data collected from quasi-experiment designs.
Elastocaloric Coupling in Polymers for Solid State Refrigeration – ECPOR
Refrigeration is used daily for the preservation of food or medicine (vaccine), for the reliability of electronic devices, as well as for the well-being of people. Based on the compression-expansion cycle of a gas, it presents some disadvantages: difficult integration in embedded systems and strong environmental impact. It is therefore necessary to develop alternative technologies in the field of solid state physics.
Transnational floodrisk management in the Rhine bassin. A historic - progressiv approach – TRANSRISK²
The objectives of the program TRANSRISK ² aim at a spatial extension of the study area of the program TRANSRISK. Besides the floods, we shall be interested in landuse changes and, particularly, in the transformations of the rivers courses. <br />A particular attention will also payed to the risks perception (communication, information), to the vulnerability, as to the contribution to a flood risk management shared on both sides of the border.<br />
Design and synthesis of antibody mimics – Mimobody
(1) the selection of CDR-fragments, (2) the assembling of selected CDRs on the cyclopeptide scaffold, (3) the in vitro screening and characterization of good candidates, (4) the grafting of NIR probes and cytotoxic triggering molecules for in vivo experiments.
Structure, dynamics and mechanism of Arpin, a novel inhibitor of the Arp2/3 complex that controls cell migration – Dynarpin
Nous étudierons la structure, la dynamique et le mécanisme d’une protéine découverte récemment au sein du consortium. Cette protéine contrôle la migration cellulaire, qui est centrale aux processus de développement ou de cicatrisation, et qui est défectueuse dans des maladies graves comme le cancer<br />
Effects of the environment on host-parasite coevolutionary conflicts: parasitic manipulation and self-medication in mosquito-human malaria associations. – EMMA
Effects of the environment on host-parasite coevolutionary conflicts: parasitic manipulation and self-medication in mosquito-human malaria associations.
ERA-NET on Cardiovascular Diseases Joint Transnational Call for Proposals 2017 (JTC 2017): “Mechanisms of early atherosclerosis and/or plaque instability in Coronary Artery Disease”
results into clinical utility. The following types of research projects are excluded from the call: [...] Accredited Health Research Institutes (Institutos de Investigación Sanitaria Acreditados, IIS), CIBER [...] register as soon as possible at https://secure.pt-dlr.de/ptoutline/app/users/login/JTC2017 , by clicking
Specification and realization of muscle identity in Drosophila – Muscle-Identity
Specification and realization of muscle identity, Model studies in Drosophila. <br />The morphological diversity of skeletal muscles underlies animal locomotion. Gene Regulatory Networks directing generic myogenesis have been decrypted in mammals, The control of each muscle morphological identity remains a fundamental and bio-medical issue, with human myopathies affecting distinct sets of muscles. <br />Muscle-Identity aimed at establishing a global view of this control, using an insect model.
A-site Manganites for mAgNetoelectrics and mulTiferroics from extreme conditionS – AMANTS
The hypotheses underpinning this AMANTS project are 1) that a variety of novel A-site based Mn oxide perovskites and related phases can be recovered from high pressure synthesis, and that these new materials will have interesting and potentially useful properties. And 2) that the new playground of “hard-soft” synthesis has an important role on the new A-site Mn2+ materials by modifying their anion lattices.
mRNA 3' end modifications by nucleotide addition: impact on translation and mRNA decay in Arabidopsis thaliana – 3'modRN
mRNA modifications and their modulation emerge as new potent regulatory processes of gene expression. The rationale of the 3' modRN project is to foster new knowledge on how mRNA modifications by nucleotide additions at 3' extremities participate in the control and reprogramming of gene expression in response to stress using Arabidopsis as a model system.
