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Application of PICh for the characterization of the RNA Polymerase III transcription regulome – PIChClassIII
RNA polymerase III plays a major role in the coordination of growth cell rate due to physiological or environmental changes, especially when cells are exposed to stress conditions. We intend to decipher the pathways (conserved from yeast to human) involved in the regulation of transcription, from th
Mitochondrial transport mechanism at the molecular level – MIT-2M
The first structure of AAC was solved in 2003 by one of the partners of the project. It is still the only atomic resolution structure of such a carrier. It shed the first light on mitochondrial carriers by showing the overall fold and the mechanism of inhibition by atractylosides, well-known poisons
– MolNanoMat
Organic solar cells face a have to overcome a fundamental hurdle: the generation of free electrons and holes from strongly bound excitons. This charge separation is possible only at the interface of two materials with different electron affinities, between a donor D and an acceptor A. Within this co