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Additifs supramoléculaires de cristallisation des transporteurs ABC de résistance à de multiples agents chimiothérapeutiques – AddX
The structure-based design of highly efficient and selective, therapeutic inhibitors, requires the knowledge of their protein targets at the atomic level, if possible in several conformations, that will reflect the different catalytic steps of a given process. This is a particularly difficult task c
Imagerie Nanométrique Femtoseconde par diffraction X cohérente – I-NanoX
A microscope resolution is limited by the illuminating wavelength. Alternative techniques that can break this barrier are not compatible with time resolved studies of ultrafast phenomena. Changing the spectral domain is a way to solve that problem. However, usual visible techniques cannot be transpo
Economies d'énergie dans les moteurs diesel : approche holistique couplant revetements DLC/Diamant et nouveau lubrifiant – ECOLUB
The reduction of energy losses, damage to surfaces and the emission of pollutants are locks for lubrication technology, particularly in the field of transport. To deal with pollution standards even more stringent (EURO 5 by 2012) and the specifications and requirements of manufacturers who still evo
SPuttering appliqué aux accumulateurs au LIThium – SPLIT
SPLIT project aims to demonstrate that a technical breakthrough is possible for the improvement of the specific capacity of Li-ion batteries. The first objective is to demonstrate the feasibility of a Lithium-ion battery with a specific energy (by weight or volume) improved by 50 % thanks to the use
In-Situ X-ray LAMinography with Bi-axial Loads for the Multiscale Investigation of DAmage Formation in Materials for Transportation – LAMBDA
In the pursuit of lighter materials and optimized thin-walled components for transportation, knowledge about the characteristic ductile damage mechanisms in metal sheets is key.As the study of damage in materials has, up to now, been focussed on proportional loading, the strain-damage interaction is
OptimAl Transport for MachIne Learning – OATMIL
In our era of steady data deluge, there is no doubt that the design of efficient techniques to extract knowledge from massive data collections or data streams has become a fundamental scientific and technological challenge bearing immense opportunities, both industrial and societal. As such, it is n
Two-Dimensional Nanomaterial-based Metasurfaces for enhanced Plasmonic Sensing – 2DPS
Surface plasmon resonance (SPR) sensors are optical sensors commonly used for real-time monitoring of molecular interactions. Graphene is the thinnest 2D material and its high charge carrier mobility makes it an attractive material for these sensors. By applying graphene layers on the top metal laye
µ-Laboratory for the Analysis and Separation of chromosomes: new tool for fast typing of bacterial, yeast, and mammalian cells – MicroLAS
We recently developed, patented, and successfully transferred a technology for DNA purification, enrichment, and separation. This technology coined µLAS involves an electric field and a counter hydrodynamic flow in viscoelastic liquids, in which transverse forces oriented toward the walls occur. The
Laser-assisted fabrication of silicone-based patches for transdermal drug release – Labricon
Silicone-based transdermal drug delivery patches are currently used in a wide range of pharmaceutical applications from hormone therapy to central nervous system related pathologies. However, their manufacture has relatively high technology barrier, impacting their price and limiting their utilizati
Prediction,reduction and study of damages impacting 3D weaving – PREDICTISS-3D
The objective of the PREDICTISS-3D project is to identify and quantify the influence of product and process parameters on the degradation of dense fabrics to reduce/eliminate mechanical performance losses of the final product (reinforcement then composite). Thus, the strategy used consists of predic
