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Modulating the gene networks underlying phenotypic robustness in plant quantitative immunity – PRobIty
Our key hypothesis is that QDR robustness emerges at the global scale from the architecture of plant and pathogen gene networks, and involves conserved genes with diverse molecular functions. The rationale behind this research is based on our preliminary results showing that regulatory changes affec
Planning and Learning to Act in Systems of Multiple Agents – plasma
WP1: PLANNING ALGORITHMS FOR CONTINUOUS MDPS WP2: PLANNING ALGORITHMS FOR STOCHASTIC GAMES WP3: FROM COMPLEX GAMES TO SIMPLER ONES WP4: MULTI-AGENT REINFORCEMENT LEARNING 1. On continuous-state MDPs w/ hierarchical information 2. Solving Dec-POMDPs as Sequential-Move Continuous-State Multi
Saturated Open-pore Foams for Innovative Tribology in Turbomachines – SOFITT
The performance of many industrial applications is largely based on the quality and reliability of the guidance and support systems (high rotational speeds, low friction torque, damping capability, etc.). In the TRIBOLUB team (Tribology of lubricated interfaces), one of the main objectives is to con
Artificial Intelligence and Dynamic Modeling tools for Future Flexible Networks – AIDY-F2N
Davidson Paris and Telecom SudParis wish to strengthen their links by setting up the ANR AIDY-F2N LabCom, a joint research laboratory dedicated to Dynamic Modeling for Next Generation networks and services. This initiative reflects the aspiration of both parties to develop and strengthen their know-
spreading of granular pastes: from the particle to end use properties – PASTFLOW
The objective should be realized by adequate modelling of the rheology of the granular paste on the basis of rheological tests, particle-based micro-structural experimental as well as simulation-based investigations. The main focus is on the development of microscale-based models, which predict the
Nanostructured Materials for Advanced Na Solid-sTate battERies – Na-MASTER
Limiting global warming requires major discoveries in energy storage technologies, leading to rechargeable batteries. The advanced synthesis and characterization techniques in synergy with modelling have enabled the discovery of materials by design, which we apply here. We will discover nanomaterial
COlloidal nanocrystal Plasmonic detector: a new paradigm for INfrared optoelectronics – COPIN
Colloidal nanocrystals are attracting an increasing interest since their recent introduction as light emitters for the last generation of displays. Their role in optoelectronics is expected to further develop, as several companies are diversifying the use of these nanoparticles for applications in o
Metabolic interactions between adipocytes and trypanosomes, a new paradigm for trypanosomiases – AdipoTryp
Trypanosoma brucei, the causative agent of HAT, was believed to spread exclusively in the fluids of its mammalian host. Breaking with this dogma, we recently shown that most parasites reside in the extravascular compartment, in particular the skin and adipose tissue, where they are in close contact
Towards a Better INtegration of the Aggressiveness of Road loads experienced bY wearing course – BINARY
The aim of the project is to develop more rational and scientific approaches for assessing the effect of traffic loads on wearing courses and for the design of these layers. To achieve these goals, the main mechanisms of deterioration of wearing courses under traffic loads, such as raveling, strippi
Exploring the P-glycoprotein-mediated efflux transport at the blood-brain barrier as a biomarker of drug-resistance in focal epilepsy – EPIFLUX
Epilepsy is one of the most common serious neurological disorders, affecting approximately 65 million people worldwide. Seizures can be controlled by antiepileptic drugs (AEDs) in most cases. However, ~30% of patients have drug-resistant epilepsy (DRE) and experience debilitating refractory seizures
