Search for a funded project
Mitochondrial and protease dysfunction in progeroid Cockayne syndrome cells and during age-associated processes – CS_AGE
We study the underlying mechanism of the altered pathway that we identified in CS cells, where oxidative and nitrosative stress (ROS/RNS) promotes overexpression of the HTRA3 protease, which results in the degradation of the key mitochondrial DNA polymerase POLG1 responsible for replication of the o
Impact of STress on uRban trEEs on ciTy air quality – sTREEt
Urban vegetation is a source of ecosystem services, such as reduction of heat island phenomenon via evapotranspiration or support for pollution deposition. Trees emit a number Biogenic Volatile Organic Compounds (BVOC) that can react with atmospheric primary pollutants to form secondary pollutants,
Lipid transport to mitochondria and contact sites formation during phosphate starvation in plants. – MiCoSLiT
Plants are organisms that are permanently subjected to numerous stresses such as high temperatures or nutrient deficiencies. Phosphate is an essential microelement for plant development, the absence of which has a considerable negative impact on agricultural yields. It is therefore important to unde
On the glassy nature of quantum disordered systems – GLADYS
Disorder is often present in condensed matter, in the form of impurities in solids, or in the random arrangement of glasses. It can have dramatic consequences, such as preventing transport or inducing extremely slow relaxation to equilibrium. In the quantum regime, the interplay between interference
MUltiscale and treFFtz for numerIcal traNsport – MUFFIN
In many applications, one is faced with the problem of solving numerically a set of transport equations, also called kinetic equations in this document. The huge difficulty attached to this task is that it may be computationally exhausting, mainly because of the high dimension and of the multi-scale
Viral Rhodopsins: Structure, Function and Next Generation Optogenetic Tools – Viral_Rhodopsins
Giant viruses have genomes and sizes comparable to those of some bacteria. Rhodopsin genes were identified in giant viruses which infect an algae of the Organic Lake, Antarctica. It is known that the algae is a major source of dimethyl sulfide which is known as a critical substance influencing ecolo
Vectorization of iridium(III) complexes using siderophore surrogates : a Trojan horse strategy against Gram-negative pathogenic bacteria – VECTRIUM
The bacterial resistance to antibiotics is a crucial issue in many countries. Urgent innovative solutions are needed to fight infections caused by nosocomial Gram-negative bacilli, such as P. aeruginosa, A. baumannii, etc. Alternatives strategies to antibiotherapy are expected to broaden the therape
Parallel Microrobot localised in a large workspace – micro-SPIDER
Current microrobots remain very large compared to the size of the objects handled, which does not allow them to reach industrial speeds. In addition, the working space of micromanipulators is often reduced because, on the one hand, the required precision levels impose a limitation of the actuator st
Photovoltaic spatial light modulators for self-activated dynamic glazing – PSLM
Dynamic glazing consists of glass with adjustable transparency in the visible and/or near infrared range.It is an effective way to control incoming solar radiation and reduce energy consumption for lighting and air conditioning in buildings. However, the deployment of existing technologies remains l
Incident Management in Crowd Gathering – GIRAFE
During the next Olympic Games in Paris 2024, France will face a major security challenge because of a series of sports events, relayed around the World, involving personalities and the public. The history of the Games and sports has unfortunately already left traces of painful events, which we have
