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Porous hydrogel under perfusion: modeling and optimization of an in vitro model of bone defect reconstruction – HydrOs
Bone is a living tissue that is subjected to various stimuli. Cells receive mechanical, chemical or biophysical signals through their environment. The information translates into a capacity to adapt to any environmental modification. In the context of bone tissue engineering (BTE), this property can
Nanostructures for Energy Optimization – NOE
The scientific aim of the Noé project is to investigate, at a fundamental level, the physics of coupled electrons and phonons transport in nanostructures, and to propose novel structures providing efficient energy conversion. On the one hand, the thermoelectric performance of Si/SiGe nanowires will
Structural optimization and preclinical validation of ABCB4 correctors – SOPREVAC
Bile secretion facilitates the digestion of dietary fats and the elimination of endogenous and exogenous toxic substances. This vital function is carried out by the liver and begins at the canalicular membrane of hepatocytes, wherein transmembrane proteins such as the ABCB4 transporter secrete phosp
Plant manganese nutrition for optimal photosynthesis and growth – PlantMan
Despite the importance of manganese (Mn) for plant growth, the mechanisms allowing the uptake of this nutrient and the pathway for its incorporation into photosystem II have been the topic of only few studies. The major aim of this project is to combine complementary approaches towards a better unde
Collaborative Transportation in the Urban Distribution – TCDU
This project aims at developing models, mechanisms, optimization methods, and a web platform for the collaboration between shippers or carriers in urban distribution. To achieve this goal, the research and development work of this project is divided into five tasks: 1. Developing centralized planni
Wasserstein Gradient Flows for Optimization and Sampling: non asymptotic properties and the non log-concave setting – WOS
An important problem in machine learning and computational statistics is to sample from an intractable target distribution. In Bayesian inference for instance, the latter corresponds to the posterior distribution of the parameters, which is known only up to an intractable normalisation constant, and
Modelling charge transport in solid dielectrics under electrical stresses and implication on materials reliability in electrical engineering – ModElec
The main objectives of this project are as follow: - The development of a transport model including physical mechanisms like polarization, recombination and diffusion; - The understanding of the conditions where some particular phenomena are observed experimentally - The validation of the transpo
Genetic, metabolic and process optimizations of hydrogen photobioproductino by the green microalga Chlamydomonas reinhardtii – Algo-H2
; ; ; ; The aim of the project is to study the hydrogen bioproduction by using photosynthesis. The model species is the green microalga Chlamydomonas reinhardtii, known for its ability to produce hydrogen thanks to a high activity Fe-Fe hydrogenase. This project has for objective to develop scientif
Original Optimized Object Oriented Numerical Model for Heterogeneous Hydrogeology – H2MNO4
The project H2MNO4 will develop numerical models for reactive transport in heterogeneous media. It defines six mathematical and computational challenges and three applications for environmental problems with societal impact. This basic research project matches perfectly well with the first topic of
Novel active inline mixer for yield stress fluids: from fundamental science to industrial processing optimization – NaiMYS
An experimental and numerical study of a novel active online mixing and heat transfer device for yield stress fluids encountered in food industry is proposed. Simple dimensional arguments indicate that, by reducing the effective length of the active mixer, one gains quadratically in the energy neede
