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Single-cell imaging of host-parasite metabolic interactions in the liver – iMET
The main focus of the project is the AMP-activated protein kinase (AMPK), the master regulator of global cellular metabolism. Because of emerging single-cell scale technologies revealing a significant spatial heterogeneity in hepatic AMPK gene expression and function, and because Plasmodium hepatic
Chloride Deregulation in Epileptic Focal Cortical Dysplasia – DYSCLO
Focal cortical dysplasia (FCD) are epileptogenic malformations of cortical development leading to drug resistant epilepsy in children. Surgical treatment is the gold standard to treat these patients and offers the unprecedented opportunity to better understand the mechanisms of epilepsy exvivo. I ha
Ecodesign of fruit and vegetable postharvest chain: Optimization of packaging and cold chain – EcoFreshChain
The objective is to design a new biodegradable cellulose packaging and combine it with refrigeration to preserve fruits and vegetables along the post-harvest chain until consumption. Several issues related to the developed packaging are studied: heat/moisture transfers and air flow within the pallet
HYPERthermophiles and their BIOMINeralization mechanism – HYPERBIOMIN
The HYPERBIOMIN project follows on from recent studies (Gorlas et al., 2015; Gorlas et al., 2018) and provides new insights into the relationships between metabolism, genetics, and high-temperature biomineralization. It has enabled the development of a realistic experimental model of hydrothermal ch
Mastering the Charge Transfers and Trapping Dynamics in Hybrid Nano-Perovskite/TMDC 2D Photodetectors – MaTra2D
Hybrid interfaces between nanocrystal (NanoX) perovskite materials and two dimensional (2D) transition dichalcogenides (TMD) hold great promises for the development of smart photodetector devices, for they combine two class of model materials displaying exceptional and complementary opto-electronic
Multiphysics Imager for Microfluidic Fuel Cells – I2MPAC
In the current objective of massive deployment of renewable energies from wind turbines and solar panels, energy storage is the most critical issue to synchronize the electrical production to the consumption. Several studies in the literature have shown how energy storage can transform intermittent
Artificial Intelligence for Health, Physical Models, Transportation and Defense – AHEAD
AI has a major impact in essentially all fields in science and humanities. At Cnam, several laboratories are developing research programs in AI. This proposal gathers actors from computer science and applied mathematics, which perform fundamental research in AI, and institutions using AI technologie
Humans and Artificial Intelligence Sharing Control and Decisions – HAISCoDe
We propose a research program of 10 PhD theses coordinated by Normandie Université (NU), which federates the most important institutions of higher education and research in Normandy. These PhD grants will be co-funded by Région Normandie, in line with its strategy for research and innovation. The
Propositional Reasoning for Large-Scale Optimization. Application to Clean Energy Mobility Issues – Massal'IA
We are in a scenario where SAT-based problem solving is highly competitive on decision problems, and Max-SAT-based approaches have been proposed for optimization problems. Max-SAT is a consolidated research line, but the performance of the solvers needs to be improved for large scale real applicatio
Algorithms, Approximations, Sparsity and Sketching for AI – AllegroAssai
AllegroAssai will address the fundamental scientific challenge of designing AI techniques endowed not only with solid statistical guarantees (to ensure their performance, fairness, privacy, etc.) but also with provable resource-efficiency (e.g. in terms of bytes and flops, which impact energy consum