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Contribution of Embryonic MACrophages in stem cell dependent hematopoiesis – EMAC
The innate immune cells called macrophages constitute prime actors at the interface amongst tissues as well as between the organism and the environment. They protect us from external/internal insults and recent studies demonstrate that they also affect patterning, tissue reshaping and metabolism. Mo
Prediction of response to systemic treatments in hepatocellular carcinoma – SYSTHEC
Background: The combination of immunotherapy (atezolizumab) and anti-angiogenic antibody (bevacizumab) is the standard of care in first line for advanced hepatocellular carcinoma (HCC) whereas tyrosine kinase inhibitors such as sorafenib/lenvatinib are used in second line. However, only a subset of
Action, Logical Reasoning and Spiking networks – ALoRS
This project involves the design of a multiagent hybrid architecture. It approaches in a multidisciplinary way the study of conceptual neural networks based on spikes called ``spiking neural networks’’ (SNN), which have the advantage not only of being biologically credible, but favorable to be model
The powers of the soul. Anthropology of the experience (XIV-XVI) – ANTHRAME
ANTHRAME offers a fundamental research project on 14th-16th century anthropology in Italy that is sorely lacking. Now, although anthropology as a science was not established until the 18th century, we use this term to designate the questioning of the nature and functions of the human being, consider
Global change impact on vulnerable carbon reservoirs: carbon sequestration and emissions in soils and waters From the Arctic To the Equator – VULCAR-FATE
Previously pristine, the Western Central Africa and Western Siberian Lowlands are now increasingly impacted by accelerated global changes with the predictable degradation of soil and groundwater systems, which could lead to potentially huge emissions of greenhouse gases (GHG) and to vast carbon (C)
Partnership for Research to Enhance Methodologies In Sustainability Science – PREMISS
Many technological innovations based on Artificial Intelligence contribute to the achievement of the sustainable development goal dedicated to industry, innovation and infrastructure (SDG 9). Among them, agent-based modeling and IoT-based crowdsourcing methods appear as promising approaches for tw
Development of the first infrared fluorescent protein with emission above 800 nm – InfraredFP800
Fluorescence cell imaging benefited from the Green Fluorescent Protein revolution in the early 1990’s, which saw the development of genetically-encoded fluorophores covering the whole visible spectrum. 15 years later, another family of fluorescent proteins (FPs) were developed from the chromophore-b
Light-transport Simulation and Machine Learning – LUCE
All optical numerical simulations based on stochastic methods are subject to intrinsic noise due to mathematical variance. Currently, denoising techniques generate artefacts and loss of detail. For predictive and reliable simulations essential for research and industry, all physical laws must be res
Measuring and Improving Explainability for AI-based Face Recognition – XAIface
Face recognition has become a key technology in our society, frequently used in multiple applications, while creating an impact in terms of privacy. As face recognition solutions based on artificial intelligence (AI) are becoming popular, it is critical to fully understand and explain how these tech
SENSing hardware burnt to feel physically non-trivial informATION – Sensation
Metrological systems are precious for quantifying our physical world. However, is there anything to recognize physically complex patterns? Smells, scents, fragrances are as many semantic notions that are difficult to quantize, but so intuitive to classify for the brain. Far from our sensors standard
