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EXploitation of planT wastes as a sustainable souRce of Anti-inflammatory Compounds for Therapeutics – EXTRACT
Chronic inflammation is associated with a broad spectrum of diseases. To combat this complex process, there is today a renewed interest in medicinal plants. It is however important to diversify biological resources in order to avoid any risk of depleting the widely used native European plants, like
Supernova Cosmology Inference – SCInf
The standard model of cosmology is confronted to two serious tensions: the current expansion rate is measured 5s faster than expectations given early cosmic age data (e.g. CMB) ; the dark energy equation of state parameter deviates at the 4s level from what is expected for a simple cosmological co
AI-Enhanced eDNA Solutions for Comprehensive Marine Biodiversity Monitoring and Reporting – ADNeIA
Human-induced pressures and climate change are having profound and growing impacts on marine ecosystems, making the continuous monitoring of biodiversity and ecological status increasingly vital. Effective monitoring requires the development, modeling, interpretation, and mapping of ecological inven
Generative Modeling of Anatomy for Quantification and Medical Image Segmentation – AnatomIA
Anatomical digital twins derived from medical images are key enablers of computer-aided diagnosis or prognosis, treatment planning or subtype discovery. We posit that recent advances in generative AI (diffusion models, LLM-like models) will bring about significant benefits towards better image-based
Study of the Volatile Communication in Petunia relying on sesquiterpenoid-induced karrikin pathway – VOLCOM
Plants use their ability to produce volatile organic compounds (VOCs) to communicate with their environment. they are also targets of VOCs released during plant-microbe and plant-plant interactions and within-plant self-signaling. In Petunia, we previously described that sesquiterpenoid VOCs are e
Macrophysiological system to improve the understanding of the action mechanisms of intra-articular therapeutics on joint tissues – MaPSJoint
There is no treatment to reverse the osteoarthritis (OA) physio-pathological process. One therapeutic option in the following years could focus on the intra-articular space to limit (1) the side effects, (2) the drug interaction, and (3) to increase therapeutic efficacy. For this, the development of
Investigating the role of claudins in gastrointestinal cancer using Artificial Intelligence – CLAUD-IA
Claudins (CLDNs) are cell surface proteins essential for maintaining cell polarity and barrier integrity. Evidence from patient samples and preclinical models shows that CLDNs are overexpressed in solid tumors, playing a key role in cancer development and metastasis, making them valuable therapeutic
Accounting for the water interconnectedness within Mediterranean catchments under water shortage crisis and global changes – AQUEDUCT
Agriculture, both rainfed and irrigated, along with forest cover, emerges as the sectors using the most water in many Mediterranean countries. To address drought and water scarcity in Mediterranean catchments, one solution is to manage water demand and use by crop and forest covers. This entails: i
Deep learning for automatic image-based biomonitoring of aquatic ecosystems – BIOINDIC-IA
Aquatic ecosystems are facing many anthropogenic pressures, highlighting the urgent need for developing innovative ecological diagnostic tools supporting the selection of robust management responses. Current diagnostic tools are able to estimate the ecological status from taxonomy-based (i.e. list o
Studying the Anonymization of Publications in Social Sciences – ETAPSS
The project will study the forms and impact of confidentiality and anonymity preservation standards on the ways of writing research in social science journals in France. It will examine how various disciplinary communities manage a notorious contradictory injunction, although little systematically s
