Search for a funded project
ECOlogical and ECONomic trade-offs of VAluable invaSions: Insights, Opportunities and Novel Solutions – EconVasions
Invasive alien species (IAS) pose serious threats to biodiversity and ecosystem health, affecting human well-being. Many of those species have multiple roles, providing both benefits and burdens to ecosystems and stakeholders. Managing these Multiple-Role invasive species (MR-IAS) involves complex t
Functional and structural studies of TSSP, a novel serine protease that diversify the functional CD4 T cell repertoire and controls spontaneous autoimmune diabetes in NOD mice – TSSP
TSSP is a new protease that controls by yet unknown mechanisms the development of self-reactive T cells directly involved in the development of autoimmune diabetes. The main objective of this project are to elucidate TSSP function and finds potential substrates. Beside fundamental knowledge in the
Computation-enabled TNT Multiplexed Sensors Fabricated by Two-Photon Stereolithography. – TNT-Sensor-IA
The TNT-Sensor-IA project aims in designing of a new generation of multiplexed array microsensors integrating a metamaterials whose porosity can be spatially programmed. Such a direct laser writing approach associates the latest advances in multiphoton stereolithography (SLA) with those in the artif
Neurotensin-polyplex: Tool for a novel gene therapy of Non Small Cell Lung Cancer – NTS-polyplex
Lung cancer is the main cause of death from cancer with 5-year survival across all stages at 15-20%. About 80% of these tumors are from non–small-cell histological type (NSCLC), including adenocarcinomas, squamous cell, and large cell carcinomas. Surgery is generally accepted as the best treatment o
Laser Plasma Electron Acceleration with kHz Lasers – HighRep
The general objective of the project is to push the development of a laser-plasma accelerator operating at kHz repetition rate. We wish to bring high-repetition rate laser-plasma accelerators to a higher level of maturity by enhancing significantly their beam quality and more specifically their stab
Observation of the territory for the understanding of the evolution of administrative boundaries and settlements. Building Geo-Historical data bases and Ontological approach. – GéoPeuple
/ / / / History of the French population and territory since the 18th century until now is quite well known at the department's and province's level. However, it is far less explored at the scale of the smallest administrative units, the communes, where the people have their everyday life. The reaso
The evolution of information use in ecology – EVO-INF-COL
Evolution by natural selection can only occur if differences among individuals are transmitted among generations, i.e. if variation is heritable. Thus, one of the great challenges in evolution is to understand the informational mechanisms underlying heritability. Recent studies in behavioral ecology
Monochain HLA class I mice, epitopes identification and preclinical tetramer calibration of interest in human diseases. – HLA
HLA class I monochain transgenic mice expressing the transgenic HLA molecules in a totally H-2 class I negative context and representative of 9 of the most frequent HLA class I alleles (A01.3, A02.01, A24.2, B08.1, B27.5, B35.1, B44.2 et Cw7.1) in all human populations, have been created. They will
Arithmetic of Shimura varieties and automorphic forms and Applications – ArShiFo
In recent years, p-adic methods (Fontaine Theory, Galois deformations) and geometric methods (deformations of varieties, local methods for Shimura varieties) have been used successfully to solve central problems of modern Number Theory. Let us mention -Serre's modularity conjecture, proven by Kh
Quantum Control for Atom Interferometry – CoQuIA
The objective of the CoQuIA project is to optimize the efficiency and robustness to environmental variations of laser beamsplitters in atomic interferometers, through novel pulse shaping methods that take advantage of unconventional optics and optimal quantum control methods. The new methods and ke
