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The environment and human health across life and social sciences – ENVIROBIOSOC
The ENVIROBIOSOC project's starting point is the acknowledgment of a situation of pluralism in the way the environment is conceived, defined and operationalised in the study of human health and disease through the biological, biomedical and social sciences. The objective is to answer the following
Ecological Fitness of Light Color Acclimation in Marine Cyanobacteria: a Cross-Scale Analysis – EFFICACY
To address the question of the respective ability of phytoplankton species to adapt in an ocean with altered spectral properties, we are studying the cyanobacterium Synechococcus, the second most abundant phytoplankton organism in the ocean and the most diverse in terms of pigmentation, with seven d
Evolution of chemoreception in relation to land-to-water transition(s) in Adephaga beetles – Evo-AquaSense
In the frame of this project, we aim to address, through an integrative approach the evolution of chemoreception in relation to land-to-water transition(s) in beetles of the coleopteran suborder Adephaga. This insect clade represents an ideal model to tackle this question as they display various lev
Surface and volume modulation of fast deforming cells and organelles – SurVol
When cells proliferate in a tumor, because the tumor is often encapsulated in a stiff basement membrane, they are compressed by their own growth. Similarly, when cells escape primary tumors, the lack of space in surrounding tissues generates compressive forces that can induce strong deformations of
Peptidergic control of pain and emotions: relaxin-3/RXFP3 modulation of descending pathways – RELAX
Le projet RELAX s’intéresse à la modulation de la douleur chronique, dans ses composantes sensorielles et affectives, et des comorbidités anxieuses ou dépressives par le système peptidergique relaxin-3/RXFP3. Il repose sur des expertises complémentaires à Bordeaux, Strasbourg et Melbourne, pour étud
Computational design of molecular catalysts for hydrogen production – CODEC
Hydrogen is regarded as a promising molecular fuel to address such problem. The design of molecular electrocatalysts for hydrogen production is important for the development of renewable energy sources that are abundant, inexpensive, and environmentally benign. In this context a number of molecular
The practice of sustainable mobility in Latin American cities: a comparative study of Bogotá (Colombia) and Lima (Peru) – MODURAL
The project examines the sustainability of commuting to work and to places of study in two Latin American metropolises (Bogotá and Lima). The latter bring together 10 million inhabitants and are marked by strong socio-residential segregation and a growth model that favours sprawl on the outskirts ra
Thioacid / Azide Ligation Applied to Nucleic acids as a new tool for chemical biology – TALAN
DNA templated chemical ligations are based on the specific pairing properties of complementary DNA strands. The latter are used to «force« the spatial proximity between chemical reactive groups of modified oligonucleotides (ODN) in order to dramatically accelerate a given reaction at very low concen
High Performance computing for quantifying climate change impacts on boreal areas – HiPerBorea
Permafrost thaw dynamics is a key factor for climatic evolution. The involved physics are highly coupled and non-linear, and simulating them at the scale of long-term monitored watersheds requires the development of spatially distributed and process oriented high performance computing tools. The fie
Organolanthanide complexes with slow magnetic relaxation – RelaxMax
The objective of the project is to make high-performance molecular magnets from organometallic compounds of lanthanides. In particular, we are interested in compounds of the sandwich type with the broad ligands of the cyclooctatrienyl (C8H8, Cot) and cyclononatetraenyl (C9H9, Cnt) type. The original
