Search for a funded project
Optical coherence tomography for REtinal Organoid imaging – OREO
Retinitis pigmentosa (RP) is a group of inherited neurodegenerative diseases that result in selective cell death of photoreceptors. <br />Human induced pluripotent stem (iPS) cell technology generates retinal organoids for disease modeling purposes, and cell-based rescue or replacement strategies. <br />High resolution imaging tools are essential to perform to monitor bioproduction of these cell cultures and to validate disease models and therapeutic solutions.
A One health study of Monkeypox: Human infection, animal reservoir, disease ecology and diagnostic tools – AFRIPOX
The understanding of monkeypox still has many grey areas: the animal reservoir is not identified, the risk factors for zoonotic and human-to-human transmission, and the ecological conditions favorable to its emergence are not fully described. Our multidisciplinary project will be grafted on the national surveillance process of monkeypox and will allow a holistic approach of this disease through multiple complementary approaches.
Elucidating the multifaceted functions of protein acetyltransferases in plant stress response and regulation of metabolism. – KatNat
The overarching aim of the KatNat project is to provide a mechanistic understanding of protein acetylation in plants, with a particular focus on investigating the enzymes that catalyze this modification (Nt- and K-acetyltransferases) and the resultant effects on proteostasis, photosynthesis, and metabolism.
A therapeutic target for ischemic related injuries, application to organ transplantation – KIRI
This project aims to design a new generation of pharmacological inhibitors capable of countering the consequences of an ischemic episode. They target a protein (serRS) that we have recently identified and implicated in the resistance of organs to ischemia. The clinical application is kidney transplantation.
Intelligent Estimation Algorithms for Smart Mobility – ArtISMo
The development of controllers with high performance and reliability for connected and autonomous vehicles (CAVs) will require real-time measurements or estimates of many variables on each vehicle. Examples of variables that are needed for feedback include: longitudinal distances, velocities and accelerations of other nearby vehicles; lateral position of the vehicle in its own lane; vehicle yaw angle; slip angle; yaw rate; steering angle; lateral acceleration; and roll angle.
Biomechanical cost quantification for wheelchair accessible cities – CapaCITIES
Locomotion with a manual wheelchair overloads the upper-limbs of the manual wheelchair users to an important stress, which varies according to the environment. To assist users in selecting the paths that preserve their upper limbs, a cost reflecting the physical demand to which the user is submitted according to the possible paths must be attributed and compared to manual wheelchair users' individual capacities.
Sustainable intensification of fruit production systems through innovative pest biological control technologies – Pest free fruit
In sub-Saharan Africa, fruit production is affected by pests that strongly impact on attaining food and nutrition security. The excessive reliance on chemicals is not sustainable, and current pest control methods are insufficient to minimize crop losses. Innovations relying on ecologically-based control become crucial to respond efficiently to sustainable fruit production, as well as societal concerns for safer and nutritionally-balanced diets, better health and environmental protection.
Inferring pest dispersal in agricultural landscapes to improve management strategies – DISLAND
Characterizing multiscale pest dispersal is key to shifting management practices, from individual decisions on the scale of the cultivated field, to collective organization and coordination of actions on a territorial scale.
Chondrite Recipe from Accretion Disk modeling and Laboratory Experiments – CRADLE
CRADLE (Chondrite Recipe from Accretion Disk modeling and Laboratory Experiments) consists in an original approach associating the development of numerical simulations modeling the physical, chemical and isotopic evolution of the protosolar disk with new observations of the isotopic compositions of primitive meteorites. These observations give access to the irradiation intensity, to the ages of the first solids formed in the disk and to their residence time in the gas.
