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MucosAl pelliCle flAvouR interactiOn & perceptioN – MACARON
MACARON will provide ground-breaking knowledge on the mechanisms of two key modalities of flavour, astringency and aroma persistence.
Role of potassium transport in rice in securing high crop yields – RiceKTrans
Crops that use nutrients more efficiently than currently available varieties can help achieve more sustainable agriculture. Potassium (K+) is the most absorbed cationic nutrient by the plant. However, little is known about the transport proteins that mediate K+ fluxes in cereals. In the proposed project, we will study K+ efflux channels and K+ transporters that enable K+ nutrition of aerial parts in rice.
The actin/spectrin scaffold shapes axonal physiology – ASHA
Our project combined cutting-edge neuronal cell biology with advanced optical and electron microscopy to discover a new function of the periodic actin/spectrin scaffold that lines the axonal plasma membrane. It forms an insulating layer that can restrict endocytosis and exocytosis along the axon shaft, limiting it to defined nanoscale locations.
HYPERthermophiles and their BIOMINeralization mechanism – HYPERBIOMIN
Interactions between hyperthermophiles and minerals undoubtedly occur in the active hydrothermal chimneys mainly composed of FeS2 pyrite. Whereas the formation of pyrite, at high temperatures (> 200°C) in the hydrothermal chimney is well known, a major stock of FeS2 is formed by a still unknown mechanism at lower temperatures (< 150°C), probably involving the living part. Thermococcales could be an important contributor to the formation of pyrite in their ecosystem.
Atmospheric River Climatology in Antarctica – ARCA
ARCA aims to describe atmospheric rivers (AR) in the polar regions by applying detection algorithms for these events on historical, current and future climate simulations. ARCA will evaluate their impact on the Antarctic surface mass balance. ARCA will also analyze the extent to which moisture transported by ARs has a particular isotopic and chemical signature and assess whether these events can be traced in ice cores.
Distant Supervision for Meeting Minutes with Rhetorical Relations – SUMM-RE
Whereas state of the art approaches to summarization treat discourse as a mere sequence of utterances, we hypothesize that the rich semantic information represented through discourse relations and structure will help to identify discourse central threads in a conversation and retrieve important semantic information such as why a certain decision was made or where there was disagreement about a certain issue.
Flame Acceleration and Transition to Detonation (FAsTD) in Narrow Channels – FASTD
The ultimate goal/aim of FAsTD is to facilitate the global energy transition by fostering the role of H2 while understanding, from a fundamental point of view, the risks associated with its widespread use, in particular the risk of deflagration-to-detonation-transition (DDT) in narrow geometries.
Mechanisms of Cell Wall Mechanosensation for the Regulation of Cell Growth – CellWallSense
This project aims to understand the molecular mechanisms of mechanosesation (force sensing) in the cell wall of fungi, and to understand how it contributes to the growth and mechanical integrity of the cell.
Tackling antimicrobial resistance in hospitals: a holistic eco-evolutionary model of resistance gene dissemination to optimize intervention strategies – ResisTrack
Designing and evaluating effective strategies against antimicrobial resistance (AMR) in hospitals is difficult. We aim at evaluating candidate interventions of antimicrobial stewardship and infection control (AS/IC) in silico. Building upon recent advances in ecology and systems biology, we will construct and calibrate an integrative ecological and evolutionary model of resistance dynamics, implementing the dissemination of ARGs, mobile genetic elements and bacteria under antmicrobial pressure.