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e-Substrates for molecular imaging in cells – NIS
Optimisation and developments of planar and micro-/nano- structured multi-dielectric stacks to i) improve the precision of single-molecule microscopy and the sensitivity of correlation imaging to follow the dynamics of molecular events occurring at the cell membrane, such as viral budding, and ii) perform fast and sensitive imaging with sub-wavelength spatial resolution.
Reaching Efficient & high-Load Operation of Anaerobic Digestion – RELOAD
Reaching Efficient & high-Load Operation of Anaerobic Digestion
Gene therapies approaches for Charcot-Marie-Tooth diseases: targeting the right cell type and compartment – GENERATE
Charcot-Marie-Tooth disease (CMT) is a rare and incurable disorder of the peripheral nervous system. There are several subtypes depending on the mutated gene and the affected cell type (neurons or Schwann cells). Gene therapy is now used as a treatment in the field of genetic neuromuscular diseases. Our Generate project aims to develop gene therapies specifically targeting the defective gene and the affected cell
Dynamics of cortical morphology during childhood development – SulcalGRIDS
Dynamics of cortical morphology during childhood development
Green process for microbial decontamination based on light and humidity control – GreenDeconta
The use of fungicides and bactericides is the main current solution to control microbial contamination in the food industry. However, this solution leads to environmental and toxicological issues. The GreenDeconta project proposes to characterize microbial responses of spoilage microorganisms to high power light treatments in order to develop a sustainable microbial decontamination process.
On the Cognitive principles underlying operational biases in the temporal domain – CoPrOBTeD
The project will (1) probe the functional locus of the effect by isolating the perceptual from the motor component of the information processing. It will test (2) the predictions that can be made according to the sensory integration hypothesis to test whether the observed effects reflect stimulus energy accumulation rather than a cognitive bias and will probe (3) whether the TME emerges from general principles governing time perception.
The actin/spectrin scaffold shapes axonal physiology – ASHA
Our project combined cutting-edge neuronal cell biology with advanced optical and electron microscopy to discover a new function of the periodic actin/spectrin scaffold that lines the axonal plasma membrane. It forms an insulating layer that can restrict endocytosis and exocytosis along the axon shaft, limiting it to defined nanoscale locations.
HYPERthermophiles and their BIOMINeralization mechanism – HYPERBIOMIN
Interactions between hyperthermophiles and minerals undoubtedly occur in the active hydrothermal chimneys mainly composed of FeS2 pyrite. Whereas the formation of pyrite, at high temperatures (> 200°C) in the hydrothermal chimney is well known, a major stock of FeS2 is formed by a still unknown mechanism at lower temperatures (< 150°C), probably involving the living part. Thermococcales could be an important contributor to the formation of pyrite in their ecosystem.
Micro-SENSors based on metal oxide sensitive layers and Metal Organic Frameworks for AIR quality monitoring at low cost - 2020 – SensMOFAir-2020
New sensitive layers, smart MOF filters and advanced electronics: the triple strategy to overcome the low selectivity of MOS sensors.
Wireless mmW communications for Railway – mmW4Rail
Spectrum scarcity is a constraint for railways. Very narrow bands are allocated in the 900 and 1900 MHz bands. This is driving the exploration of mm bands in 5G developments and beyond for specific needs. This is planned in well-defined areas (stations, marshalling yards, high-speed lines) and for specific use cases such as virtual train coupling, platooning, remote train driving, maintenance data downloading, etc.
