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Functional aspects and physisopathological impact of intracytoplasmic lipid inclusions in mycobacteria – ILIome
Infection with M.tb leads to the formation of granulomas in the lung, where some of the infected macrophages accumulate lipids in lipid bodies (LB) giving the cells a foamy appearance. In such foamy macrophages (FM), M.tb is able to hydrolyze host lipids into fatty acids that are reused as lipid res
Adaptive Characteristic Mapping Method for the Euler Equations – CM2E
We develop a numerical method for transport dominted problems with extreme resolution capabilities using the characteristic flow map. extremely high resolution capabilities of the scheme obtained by decomposing the flow map and appropriate remapping X.-Y. Yin, K. Schneider and J.-C. Nave. A Charac
Getting the record from the disc: A study of the Milky Way disc with WEAVE and Gaia – MWDisc
The WEAVE (WHT Enhanced Area Velocity Explorer) survey, is a five- to seven-year project of spectroscopic observations to be carried out from the William Hershel Telescope at Roque de los Muchachos Observatory (Canary Islands, Spain). The Galactic Archaeology (GA) part of this project, from which
History and Archaeology of Monasteries and Ecclesiastical sites in the Eastern Adriatic (IVth-XIIth c.) – MONACORALE
The research project “MONACORALE – History and Archaeology of Monasteries and Ecclesiastical sites in the Eastern Adriatic (4th-12th c.)”, is born from the collaboration of French, Croatian and Italian researchers working on archives, texts and ecclesial, and notably monastic sites of the Istrian an
high strain RAte, TEmperature and Small-scale mechanical properties of materials – RATES
The vast majority of work on scaling effects (in the sense of mechanical properties) in metallic materials is limited to low strain rates ( < 0.01 /s) and moderate temperatures ( < 200 °C). The field of very high strain rates and high temperatures is still relatively unexplored, especially at small
3D dAta DriVEn iNvestigation of faTigUe cRack growth with ovErload effects – ADVENTURE
Reliable models are essential in all areas where cracking is a safety issue. Although structural materials are subjected to variable amplitude fatigue loading, the effect of overloads remains difficult to predict. After an overload, the relationship between the crack growth rate before overload and
Architecture of complex systems in intelligent immersion – ArchiTOOL
To address the limitations of current systems engineering tools, the project is based on three complementary technological levers: virtual reality, intelligent assistance, and unified interactive modeling. On one hand, an immersive virtual reality environment was developed to replace low expressiven
Coherence of the digital twins for the industry of the future: Modeling, visualization and interaction with 4D digital mockups coupled with physical systems – COHERENCE4D
Introduced at the beginning of the century by NASA, the concept of the digital twin is now at the heart of digitalization issues and appears to be an essential element for meeting the challenges of the fourth industrial revolution. The digital twin is a dynamic virtual representation that can follow
Simulation Analytics and Metamodel-based solutions for Optimization, Uncertainty and Reliability AnalysIs – SAMOURAI
The project's main objectives are to develop innovative simulation and surrogate-based optimization methodologies while pushing back their current limits of performance and applicability, guided by real-world applications. These applications are related to the design and risk assessment of critical
Droplet-based Textile Microfluidics for High-Throughput Organoids Screening – DROMOS
The project aims to develop a new type of platform for screening from cellular spheroids. This platform is based on the microfluidic technology of drops, or more precisely of «plugs«, i.e. drops strongly confined in a cylindrical channel. Each channel contains a «train« with several series of drops
