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Deciphering tolerance breakdown in a human B-cell mediated autoimmune disease – Autoimmuni-B
Which deregulation occurs in human autoimmune diseases and what is the dynamic contribution of each subset of B cells in this process is the central question of this proposal. We will take advantage of a unique model, the antibody-mediated autoimmune disease immune thrombocytopenia (ITP), in which different disease treatments and outcomes delineate distinct pathogenic effector subsets and for which splenectomy allows the study of tolerance breakdown during an immune response in a lymphoid organ.
Three terminal tandem HEterojunction on interdigitated back contacts SIlicon Solar cell – THESIS
The conversion efficiency for Si-based photovoltaics (PV) has reached a record 26.7%, which is close to the theoretical limit. To go beyond this, THESIS aims to benefit from the combination of the maturity of Si technology with the potential yield gains associated with emerging PV, through the development of a new PV tandem. This involves the integration of a perovskite solar cell stacked on a Si solar cell with interdigital contacts on the back side.
Catalysts with Metal-Ligand Cooperation for Sustainable Energy – CatEngy
Catalysts with Metal-Ligand Cooperation for Sustainable Energy (CatEngy) project addresses some challenges of a sustainable chemistry and production of alternative energy source for future generations. Hydrogen and alcohols are potential energy careers. Storage of dihydrogen H2 under safe and easy to handle form is a challenge to overcome for the development of hydrogen-based energies and chemical storage (i.e. dissociated hydrogen) is a topic of intense research receiving strong interest.
Southern natural heritage: a small-scale global history – PANSER
PANSER aims to analyze how, from Africa to Asia, from 1900 to nowadays, «experts« have been moving from one protected area to another and as a result, have been shaping an Afro-Asian bio-heritage area. Through six case studies (Congo, Ethiopia, Seychelles, Vietnam, Cambodia, Malaysia), research intends to investigate the trajectories of these heritage-makers, study the negotiations and struggles enrooted into nature, and in doing so to explore a small-scale global history of natural heritage.
Ecclesiastical Organisation and Christian Topography of the Lower Danube during Late Antiquity (3rd-8th Centuries AD) – DANUBIUS
Ecclesiastical Organisation and Christian Topography of the Lower Danube during Late Antiquity (3rd-8th Centuries AD)
Aluminium, Architecture & Heritage, XX-XXIst centuries – ARCHIPAL
Lightweight, resistant, infinitely recyclable, aluminium emerged as a material emblematic of modernity thanks to its technical characteristics. It inspired architects because it offers artistic experimentation a range of possibilities that is particularly stimulating both in terms of the variety of forms that can be achieved and the aspects and the colors available. This facility to disguise oneself is questioned from the point of view of the history and the sociology of techniques.
At the edges of kinship : origins and new family configurations – ORIGINES
What meaning should be given to the ties uniting people who, without being relatives in the legal sense, are connected by the circumstances of a procreative act? This multidisciplinary project (history, social anthropology, sociology and law) regards the links - real or fantasized - created by the relation to «origins« in the new family configurations (adoption, assisted reproduction, surrogacy).
Amino Acid Asymmetry – AAAs
Proteins and nucleic acids are functional biopolymers composed of L-amino acids and D ribose subunits that break chiral symmetry. The origin of the symmetry-breaking event is unknown. The AAAs project proposes to characterize chiroptical properties of chiral amino acids and their volatile aldehyde precursor molecules for the first time in the gas phase, where the initial asymmetric interactions between chiral photons and life’s molecular subunit precursors are assumed to occur.
Working in the margin? Collaborative spaces as nodes of a new mobility system outside metropolis – PERI_WORK
Collaborative workspaces as nodes of a new mobility system outside metropolises
New POLlutant EMIssions from modern Euro 6 CarS: atmospheric transformations and implications for urban air quality and health – POLEMICS
The demand for urban mobility is steadily increasing and the growing number of vehicles in cities poses major environmental and health issues. POLEMICS addresses urgent questions on new Euro6 car emissions. The consortium composed by analytical mass spectrometry experts, toxicologists and air quality modellers will investigate the nature, the fate and the impacts on air quality and health (toxicity and genotoxicity) of Euro 6 emissions combining in laboratory and real world measurements.
