Search for a funded project
CONFLICTS BETWEEN LARGE MARINE PREDATORS AND HUMANS: THE GENESIS AND MANAGEMENT OF PROBLEM INDIVIDUALS – ETHO-PREDATOR
ETHO-PREDATOR will investigate the existence of personalities (temperaments) within two taxa, killer whales and bullsharks, and elucidate the biological and ecological mechanisms driving the emergence of problem individuals (PIs) in human-marine top predator conflicts. Our results will advance sustainable management and conservation of large marine predators involved in Human-Wildlife conflicts.
eXplaining Competency and Autonomy development in Learning Environments – xCALE
Our main objective in this project is to investigate how to support successfully self-regulated learning at a large scale, with an approach that aims to estimate online acquired skills levels and metacognitive levels about students to provide appropriate interventions.
Restriction of SARS-CoV2 replication by non-coding and unreferenced genes in human cells – DARK-COVID
Our hypothesis is that human cells express unique sets of non-coding and unreferenced genes that exhibit potent inhibitory activities against SARS-CoV2. Our objectives are to identify and characterize these genes in human cells by combining an original approach that compares the total transcriptome changes in virally infected and neighboring uninfected cells with exhaustive and reference-free transcriptome analyses, loss-of-function screening strategies and mechanistic studies.
Development of a new concept in plant protection applied to apple scab – ENFIN!
The objective of the ENFIN! project is to test the effectiveness of a breakthrough technical itinerary in apple orchards. ENFIN! is based on two innovations patented by INRAE which exploit the diversity of the fungus responsible for apple scab: one renders the pathogen non-virulent in the manner of an autocidal control, the other reduces the symptoms of the disease
Expanding the repertoire of STructurally conserved AviRulence proteins in plant pathogenic fungi to propose knowledge-driven plant resistance management – STARlep
The STARlep project aims at exploring structural and functional diversity among L. maculans avirulence (AVR) proteins to propose knowledge-driven plant resistance management. It includes structural characterisation of L. maculans AVR and their classification into structural families, determination of the plant proteins and cellular processes targeted by the AVR proteins and identification of resistances recognizing effectors with contrasted structures and functional mechanisms.
Genetic and Metabolic Determinants of Elevated Lipoprotein (a) – KRINGLE2
One in five individuals displays elevated lipoprotein (a) [Lp(a)], a highly atherogenic lipoprotein resembling low-density lipoproteins (LDL). Pathophysiological, epidemiological and genetic studies demonstrate that when circulating Lp(a) levels are high (above 125 nmol/L), cardiovascular event rates sharply increase.
Towards clinical investigation on the use of Mineralocorticoid Receptor Antagonist for wet Age-Related Macular Degeneration – MR-A-MD
Wet AMD remains a major cause of vision loss despite anti-VEGF therapy due to frequent re-injections, geographic atrophy, fibrosis and no effects on neovessel growth. Based on pre clinical results and pilote clinical study, we propose an alternative therapy using antagonism of mineralocorticoid receptors (MRA).<br />MR-A-MD aims at developing a local formulation of spironolactone and identifying molecular and imaging markers to optimize the design of a prospective randomized clinical trial.
Strengthening the antifungal efficiency of natural glycolipids for rapeseed protection in field – SHIELD
Formulation of rhamnolipids, natural glycolipids, to protect rapeseed against the dominant disease sclerotinia under field conditions
From health crisis to political crisis? A study on the politicization processes in France hit by the Covid-19 epidemic – COVIPOL
How is the health, economic and social crisis caused by Covid-19 affecting citizens' political attitudes and their relationship to voting and democracy?<br />This project aims at providing a better understanding of how crises change political attitudes, through an analysis of politicization processes related to the current health crisis. It starts from the central assumption that work is a main space of socialization to politics.
Epidemic of Covid-19: Study of the Impact and the Profiles at Risk of Suicide among Students – ECLIPSE
Students ‘vulnerability to mental health problems is now certain, and the health crisis context of the COVID-19 epidemic may have further weakened this situation. While there is uncertainty about suicide risk in this period, it is likely that suicide risk will become a more pressing concern as the pandemic continues and has longer-term effects on fragile groups such as students.
