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Mitochondrial transport mechanism at the molecular level – MIT-2M
The first structure of AAC was solved in 2003 by one of the partners of the project. It is still the only atomic resolution structure of such a carrier. It shed the first light on mitochondrial carriers by showing the overall fold and the mechanism of inhibition by atractylosides, well-known poisons
Application of PICh for the characterization of the RNA Polymerase III transcription regulome – PIChClassIII
RNA polymerase III plays a major role in the coordination of growth cell rate due to physiological or environmental changes, especially when cells are exposed to stress conditions. We intend to decipher the pathways (conserved from yeast to human) involved in the regulation of transcription, from th
Contactless inspection of tubular inner surfaces – InSITUbes
Tubular structures are used in most industrial sectors. Present in numerous industrial processes for the transport of reagents, their injection or cooling devices, they are found especially in the agro-food, energy, pharmaceutical, chemical, aerospace, transportation or biomedical. For many year
2D heteroepitaxial BN/ epigraphene /SiC films for electronics – BONNEG
The goal of this project is to validate the working principle of tunnel field effect transistors built from 2-dimensional heteroepitaxial boron nitride/ epigraphene /SiC films, with a viable large scale integration scheme. The first step is to produce ultrathin homogeneous BN films by deposition o
3D Bragg ptychography: Developments for metallic nano-twinned thin films – PtyMet
The project is built on two objectives: the first concerns materials, the second is more methodological. Indeed, we want to develop nano-twinned gold thin films. We believe that these films will combine ductility (because gold is initially ductile and that the twins can migrate or enlarge), mechanic
3D Fe/Cu-PEROVskites for electrochemically assisted TREATment of wastewaters – PEROV-TREAT
PEROV-TREAT aims at integrating perovskite-based porous materials in an electrochemical process for wastewater treatment in order to improve the treatment of persistent micropollutants and the management of antibiotic resistance, with the objective of reusing treated wastewaters. The application wil
3D modeling of Digital Mock-Up based on the integration of heterogeneous data – METIS
This project is in the field of reverse engineering, which is widely used in the manufacturing industry to capitalize on knowledge that has not yet been and is now becoming crucial to develop products. There are many applications, such as reverse engineering of existing products in order to modify /
5G-REalistic radio channel MOdels enabled system evaluation for RAilway environments – 5G-REMORA
The development of safe and secure applications such as remote driving, remote diagnostics, platooning of trains and autonomous vehicles in railway context has led to an unprecedented need for reliable radio links. The Future Railway Mobile Communication System (FRMCS) is designed at European level
: Cavities for Optical Clocks – CaOC
Optical lattice clocks (OLCs) have progressed rapidly since the initial proposal in 2002, they now outperform even the best microwave clocks realizing the current definition of the SI second, as well as single ion optical clocks, thus becoming the best frequency references. While several groups worl
A CONVENIENT APPROACH TO GLYCOAMPHIPHILES AS ACTIVE LAYERS OF LCD-BASED BIOSENSORS – SWEET-DISPLAY
In our bodies, as in plants and bacteria, certain molecules called glycoconjugates play an essential role. These molecules are formed of sugars attached to proteins or fats, and are found in particular on the surface of cells. They enable communication between cells, recognition of microbes, and par
