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mGluR5 nanobodies as innovative therapeutic tools for Alzheimer’s disease – NanoThALZ
Metabotropic glutamate receptor 5 (mGluR5) is highly expressed in brain regions responsible for memory and learning. Aberrant mGluR5 signaling and associated synaptic failure are now considered as an
mGlu7 heterodimers: existence in vivo and physiological implications – HeteroGlu7
Glutamate acts on eight G protein-coupled receptors that regulate the activity of many synapses. These receptors are obligate dimers, and have so far been considered only as homodimers. We have shown
investigating MAssive Galaxy Emergence & Early Evolution – iMAGE
During the first three billion years of the Universe, massive galaxies display the most fascinating phases in galaxy evolution, with extreme variations of their star-formation and radical changes of t
integrating High resolution Data from Remote sensing And land surface models for Transpiration and Evaporation mapping – HiDRATE
Current Earth Observation systems provide operational tools to derive areal evapotranspiration (ET) for drought monitoring and sustainable management of agricultural water. But partitioning ET into tr
in vivo catalysis by artificial enzymes for aldehydes production – INCA
New strategies in organic synthesis, following the principles of green chemistry, are required to reach sustainability. In this context, biocatalysis is the most promising approach, while man-made cat
immunoregulation regeneration – iREG2
Integral tissue regeneration is a major unmet medical need.The recent pivotal work of the coordinator provides a unique clinical situation of induced de novo generation of trachea and bronchus. Local
hydrodynamic and acoustic cavitation for the process intensification – CAPRI
Cavitation phenomena can be used to intensify processes involving physical or chemical transformations. Although acoustic cavitation has been studied for a long time for applications in chemistry, wat
functionalized and adherent biomimetic apatite coating for PEEK implants – Ca-PEEK
Medical implants replace dysfunctional or missing body parts to maintain physiological functions. The associated market is growing by 4%/year. However, the key factor restraining the market is high im
e-BdF: the digital bibliographical library of the 19th century, to shed a new light on the history of literature – e-BdF
A digital edition of the [Bibliographie de la France], to shed a new light on the History of French Literature (1811-1914)
dsRNA-based detection of viruses – VDOSAGE
Double-stranded RNA (dsRNA) is a hallmark of a vast majority of viral infections, it is produced by RNA viruses during replication and by DNA viruses upon convergent transcription. Despite being large