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AluACA RNAs, a novel class of human box H/ACA noncoding RNAs – AluACA
Our group has a long-standing interest in understanding of the functional complexity of box C/D and H/ACA small nucleolar and Cajal body-specific RNPs (snoRNPs and scaRNPs). During studying a group of human C/D and H/ACA RNPs which are associated with WDR79, we discovered a new class of human H/ACA RNPs, called the AluACA RNPs. The AluACA RNAs are processed from intronic Alu repetitive sequences.
Aluminium Nanoflakes for Propulsion Application – ANPA
Energetic materials play a key role in many applications both civilian and military. The objective of the ANPA project is to synthesize, characterize and understand the mechanisms of oxidation of nano
An Integrated Structural Biology Approach to the study of oncogenic deltaNp73-alpha stabilization induced by the IKK-beta kinase – IKKp73
The IKKß kinase phosphorylates the oncogenic deltaNp73alpha isoform (a member of the p53 tumor suppressor family and named Dp73 from here on) at Ser422. This phosphorylation event promotes the formation of a tight complex between IKKß and Dp73, which associates to the promoters of p53-regulated genes leading to silencing of gene expression. The project aims at characterizing the IKKß/Dp73 complex using an integrated Structural Biology approach.
An integrated test of Natural-Enemy mediated tree BEta-DIVersity across South American rain forests – NEBEDIV
Tropical plant diversity is extraordinarily high both at local and regional scales, including a significant component of beta-diversity, or the turnover in species composition across habitats and regions. Yet we still know little about the relative roles of biogeography, abiotic factors, and biotic factors in shaping tropical community composition. The NEBEDIV project represents a comprehensive evaluation of tropical forest beta-diversity across broad geographic and environmental gradients.
An international effort to understand FSHD muscular dystrophy epigenetics – inter-FSHD-epigen
Despite the fact they constitute two thirds of the human genome, repetitive sequences are largely ignored. FSHD is an autosomal dominant disorder with a strong epigenetic component. Unlike the majorit
Analysis of Fiscal Policy Mutipliers – AMF
The aim of this project is to analyze the macroeconomic consequences of fiscal policy and to evaluate their effects.
Analysis, Synthesis and Transformations by Reassignment, EMD and Synchrosqueezing – ASTRES
Disentangling multicomponent signals and images into elementary constitutive parts is an important problem because of its ubiquity in many areas of science and technology. This however remains a chall
Anthropology territories - Interpretation of heritage – ANTIMOINE
The contribution of ANTIMOINE projects concernes «Digital Humanities« because it focuses on the study of innovative tools for participatory construction and dissimination of heritage ; the design of these tools is based on three areas : linguistics, data science and virtual reality.
Anthropomorphic Action Planning and Understanding – ENTRACTE
The ENTRACTE project addresses the problem of motion planning for anthropomorphic systems, and more generally, the problem of manipulation path planning. The associated trajectories are living in well
Anti-Bacterial Immune Regulation – Abir
Infections by intracellular bacterial pathogens of the genus Salmonella spp. and Listeria spp. remain leading causes of foodborne illnesses. For instance, typhoid fever, a disease caused by Salmonella