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Photographic cOntents Exploration through iMmersive Environments – POEME
Innovative tools for exploring large collections of images
Analysis of the heritability of epigenetic traces in clonality context – methylclonome
Analysis of epigenteic marks that confer heritable and reversible adaptive traits. Analysis of methyl groups on the full genome that guides non mendellian heredity: example of a parthenogenetic species that produces distinct morphotypes and variant in clonality context.
Integrated multi-approach study of the central mechanisms underlying the hormonal control of female reproductive behaviors – NEUROFEM
Behaviors essential for reproduction by females constitute a chain of behavioral responses beginning with courtship, leading to copulation (lordosis), which in turn ultimately leads to maternal behavi
Depression and Nutrition – MoodFood
An alternative health care perspective to treat major depressive disorder is to develop preventive strategies to limit its progress. The estimated ratio of n-6:n-3 n-3 Poly-Unsaturated-Fatty-Acids (PUFA) in a typical Western diet is around 20:1, in contrast with the optimal 1:4 ratio. The risk of developing depression has been associated to low diet n-3 PUFA content.
Dissection of an inhibitory gate that controls information flow in the hippocampus – CA2Gate
La région CA2 de l’hippocampe, une structure impliquée dans la mémoire, a été complètement ignorée. Nous proposons d’étudier cette région, en focalisant notre attention sur la transmission inhibitrice qui semble jouer un rôle important dans cette région du cerveau.
Superresolution imaging of the tripartite synapse – SUPERtri
Research on glia cells, in particular astrocytes in the brain, has in recent years led to a thorough reappraisal of their role for brain function. The concept of the “tripartite synapse”, recognizes the important role that astrocytes play for regulating information transfer at synapses in the central nervous system. The project aims to substantially advance our understanding of the dynamic interactions between astrocytes and neurons at synapses.
Investigating the roles of cilia during mammalian neurogenesis – CiliaStem
Ciliopathies are human pathologies characterized by ciliary deficiency and whose major clinical features include brain defects. We are focusing our efforts to decipher the molecular mechanisms involved in these pathologies by studying mouse genetic models.
Elucidating the mechanical role of internal tissues in morphogenesis – MechInMorph
The overarching aim of this proposal is to elucidate the mechanical role of internal tissues in morphogenesis. Over the past 20 years, numerous studies have demonstrated that morphogenetic gradients c
Pregnancy, Air Pollution, Epigenetics, and Respiratory health – PAPER
The PAPER (Pregnancy, Air Pollution, Epigenetics and Respiratory health) project builds on the hypothesis that environmental exposures during the developmental period can influence foetal development and lead to programming of health in childhood and later on. <br />
Stochastic gene expression and phenotypic variability in yeast adaptation – NOISYEAST
This project aims at exploring a mode of yeast adaptation still little studied: modulation of variability (or «noise«) in gene expression.