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RATIOnal design of hierarchical porous electrodes and of enzymes for biofuel CELLS applications – RATIOCELLS
Developping new sources of energy to power implanted medical sensors
Electrochemistry and LIpid architectures for Peptide Translocation Investigation and Control – ELIPTIC
Transport of active molecules across biological membranes is a central issue for the success of many pharmaceutical strategies such as epigenetic therapies which opens new perspectives in cancer treatments.
Role of continental configuration in the development of worldwide ANOXia in bottom ocean SEAwater. – Anox-Sea
Understanding the mechanisms and the thresholds that trigger global anoxia in the oceans during abrupt warming events represents a major issue in the current context of atmospheric CO2 increase. These events disappear during the major paleogeographic changes that characterize the Late Cretaceous, highlighting a possible role of paleogeography through changes in oceanic circulation and continental weathering.
Pi-Radicals as Building Blocks for Electron-Responsive Molecular materials and Organized Assemblies – PRIMO
The aim of this proposal is to explore a new concept of redox-responsive molecular materials. Electron-responsive switchable architectures have long been recognized as the most straightforward and viable choice to produce practical devices; however, efficiently designing such systems on the molecular scale remains a challenge.
alpha-Aminoperoxides: from titanium chemistry to complex nitrogen-containing molecules – ACTiMAC
We are exploring the reactivity of alpha-aminoendoperoxides. These reactive molecules have been little studied, in spite of their high potential for the development of novel applications in organic synthesis and, in particular, the preparation of complex nitrogen-containing systems which are included in the structures of many natural products and bioactive molecules.
Polyhydride IRON complexes and HYdrofunctionalized Catalysis – IRONHYC
The goals of the project are (i) to prepare new polyhydride iron complexes, and (ii) to use them in homogeneous hydrofunctionalization catalysis, more particularly of carbon dioxide (CO2), and industrial applications in an eco-compatible and green way.
Cationic Boranes and boronic compounds: New tools for fluorination and radiofluorination – BoBo
Boron and fluorides are easily forming strong bonds, although the latter can be smoothly broken in water. This project aims at making this bond more stable these bonds in a range of media, including biological ones. Yet we are willing to maintain the ability to release the fluoride at will in order to perform fluorination and radiofluorination.
Megathrust earthquakes in Chile: The 2010 Maule Earthquake (Mw 8.8) and sismo-tectonic implications – MEGA-Chile
To move ahead on the understanding of the mechanics of megathrust earthquakes we propose to study the 2010 Mw8.8 Maule earthquake in every possible detail and to put it into the perspective of the geo
Air-Sea Interaction and Coupling with Submesoscale structures in the MEDiterranean – ASICS-MED
Ocean convection is a key process in the exchanges between the upper and deep ocean layers and is a driver of the thermohaline circulation. It occurs in only few specific regions on the globe, of which the north-western Mediterrenean during the Winter period. The ASICS-MED project has addressed the role of the interactions between the ocean and the atmosphere in these events.
Click strategies for multifunctional anti-Alzheimer agents – Multi-click
The aim of this project is to synthesize multi-target directed ligands (MTDLs) aimed at the treatment of Alzheimer disease (AD) through the assembly of high-affinity precursors via click chemistry.