Search
Innovative Multijunction with movPe and Epitaxy at low-TemperatUre for Solar – IMPETUS
Multijunction solar cells hold by far the highest conversion efficiency for any photovoltaic cell, with a 44% efficiency record under concentration, and offer a viable solution for photovoltaic power
Neural Control of Appetite and Metabolism by Neural Cell Adhesion Molecule – NCAM2
Context. Occidental countries have to face a dramatic expansion of metabolic diseases, including obesity and diabetes, representing a major health burden in industrialized societies. The rapid increas
Toward the therapy of AUNA1 auditory neuropathy – Diaphanous
The Diaphanous homolog 3 (DIAPH3) gene is responsible for the autosomal dominant nonsyndromic auditory neuropathy 1 (AUNA1). DIAPH3 belongs to the formin related family, i.e, it is activated by Rho-GTPases and stabilizes the cytoskeleton. Strikingly, the DIAPH3 gene mutation leads to the overexpression of the DIAPH3 protein. <br />Here, we propose to decipher the mechanism responsible for AUNA1 from the molecular signaling pathways to the system level in order to envision future therapies. <br />
Study of familial myeloproliferative neoplasms : search for genetic abnormalities and their functions. – GERMPN
Myeloproliferative neoplasms (MPN) are clonal malignancies caused by genetic defects that occur in the hematopoietic stem cell and result in overproduction of one or several myeloid lineages (i.e. ery
Discoidin Domain receptor 2 signaling in liver sinusoidal endothelial cells during fibrosis – DDR2LSEC
The liver is a vital organ and a site of extraordinary exchange between blood from digestion and hepatocytes. These exchanges are made possible by a unique architecture of the liver capillaries, also
From the characterization of factors determining paralytic toxin (PST) accumulation by the oyster Crassostrea gigas to risk assessment for human health within its social context – ACCUTOX
Harmful Algal Blooms (HABs) have major socio-economic and ecological impacts, by making the cultivated and/or fished shellfish unsuitable for consumption, by disrupting the balance of populations, by
From mechanistic studies to environmental friendly process: new methodologies for Cu or Fe catalyzed C-C bond formation – CuFeCCBond
The ANR is designed to support a research project in the field of organometallic catalysis, namely: CuFeCCBond. The proposed research program is within the general framework of green syntheses for su
Oxidative cleavage of bio-sourced diols – COUPOX
Oxidation reactions are widely practiced in the Chemical Industry and products obtained through this method represent a huge market. The transformation of alkenes through oxidation processes leads to
Impact of antenatal exposure to pesticides on neurophysiological functions (sleep, respiration) of preterm neonates – PHYSIOMECO
Although the health effects of pesticides in man following acute intoxication are well known, little is known about the effects of chronic low-dose exposure. Furthermore, the paradigm concerning the d
Impact of environmental chemicals on the mechanisms of disease progression of liver steatosis – STEATOX
Several studies are pointing out that western lifestyle (high-fat diet, alcohol consumption, cigarette smoking) cannot explain by itself the increasing incidence of cancers, especially of hepatocellul