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p-adic Hodge theory and beyond – ThéHopaD
This project lies in the area of arithmetic and algebraic geometry. It aims at advancing both arithmetic and geometric aspects of $p$-adic Hodge theory by focusing on two of the deepest and most chall
Physiological Consequences of Fragile X Mental Retardation Protein Sumoylation – SUMO-ID
Alteration of protein modification in nerve cells may lead to developmental defects and therefore to intellectual disabilities.
Signalling network associated with serotonin 5-HT6 receptor : a new target for the treatment of cognitive deficits in neurological and psychiatric disorders – SERO6COGNET
The serotonin 5-HT6 receptopr, a new target for treating cognitive deficits of schizophrenia
Liquidity effects, risk control and BSDEs – LIQUIRISK
From the financial point of view, the purpose of this proposal is to take into consideration liquidity market frictions and risk management constraints in hedging and optimal allocation problems. From
Modelling of protein hydration water for small-angle scattering – HYDROSAS
The knowledge of atomic structures of biomacromolecular complexes is essential to understand life at a molecular level. To this end combined approaches (crystallography/NMR with electron microscopy and/or small angle scattering) have been developed recently. In these combined approaches the quality and accuracy of atomic models depends on the influence of the hydration shell surrounding the molecules.
Mechanisms of CAG trinucleotide repeat expansion in Huntington's disease – HexpanD
Up to 20 genetic disorders, including Huntington’s disease, result from the expansions of trinucleotide repeats. These expansions are unstable in patients somatic cells, which accelerates disease progression. The mechanism of repeat instability is elusive and is the focus of our research studies
Taming Hard Reachability Problems for Counter Systems – REACHARD
It is studying the reachability problems for counter systems.
From Manuscript to Image : Towards a Cultural Genetics ». – ARCHIZ
The ARCHIZ project seeks to provide a synthetic vision of the scientific archives on Émile Zola's work (texts, images, manuscripts…). Its practical objective is to create a web site which, in one single location, provides all these archives and makes them accessible for the general public, teachers and professors, as well as the research community. It aims to create both a tool of documentation and a reference site for research.
Role of the interactions between motoneurones and oligodendrocyte progenitor cells during the formation of spinal motor networks – OLIGOSPINE
Elucidation du rôle des interactions entre neurone et progéniteurs d’oligodendrocytes dans l’émergence des premiers réseaux locomoteurs de la moelle épinière. Influence de l’activité et des libérations de neurotransmetteurs sur les progéniteurs d’oligodendrocytes.
Structural determinants of lactococcal Siphoviridae phages infectivity – Lacto-Phages
Phages with tails (Caudovirales) belong to three families, among which Siphoviridae possess a non contractile tail terminated by a tail tip or a baseplate serving for phage adsorption on its host. Whi