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Adapting T. reesei cellulolytic enzymes for Simultaneous Saccharification and Fermentation – ACTIFE
Combination of lignocellulosic biomass hydrolysis and fermentation steps can lead to lower process costs for the 2nd generation bio-ethanol industry, but also brings constraints to the enzymes' activities. The objective of this project is to adapt several enzymes to these constraints.
Understanding decision-making from the dynamics of large neural populations in behaving zebrafish – ERASYSBIO (ANR-09-SYSB-0009)
One of the central goals in brain research is the elucidation of the dynamic interactions among neurons and circuits underlying cognitive processes. In this project we focus on decision making as an e
Living with uninvited guests -comparing plant and animal responses to endocytic invasions – ERASYSBIO (ANR-09-SYSB-0007)
Salmonella are Gram-negative bacterial facultative endopathogens capable of infecting an unusually wide range of organisms and the causative agent of various human diseases, from enteritis to typhoid
Integration of computational modelling with transcription and gene essentiality profiling of both MTB bacillus and infected human dendritic cells and macrophages to understand molecular interaction networks involved in the host pathogen cross-talk – ERASYSBIO (ANR-09-SYSB-0005)
Mycobacterium tuberculosis is a major pathogen of man. Drug treatment is available for human disease but it takes six months, which is impractical in developing world settings where TB is most common.
Fruit Integrative Modelling – ERASYsBIO (ANR-09-SYSB-0003)
Commercial fruit production is under significant pressure from environmental stresses, but also by changes in the consumer’s demand for taste and nutritional value. One key goal of fruit biology is th
Circadian and cell cycle clock systems in cancer – ERASYsBIO (ANR-09-SYSB-0002)
Mammalian cells are endowed with biological oscillators which time their activities. The circadian clock (circa, about; dies, day) generates a 24-hour rhythm which controls both cellular metabolism an
Biophysical Modelling of the Uterine Electromyogram for understanding and preventing PreTerm Labor – ERASYsBIO (ANR-09-SYSB-0001)
The aim of the BioMod UE_PTL project is to better understand the links existing between the microscopic phenomenon involved in uterine contractility leading to labour and the macroscopic electrical ac
Injectable bioresorbable and antibacterial composite for bone regeneration – BIOSINJECT
Due to the worldwide increase in life expectancy and evolution towards better life quality for patient there is an increasing demand in the development of biomaterials especially for orthopedic applic
Aortic stent-graft placement by augmented angio-navigation – ANGIOVISION
The abdominal aortic aneurysm (AAA) is the most common aortic aneurysm. The endovascular treatment of AAA (EVAR - EndoVascular Aneurism Repair) has become an alternative therapy to conventional open s
Adaptable, configurable and upgradable tool for the generation of individualized therapeutic applications in cognitive rehabilitation – AGATHE
Cognitive impairments are a major factor of loss of autonomy and dependence. They constitute a major problem of public health whose care is difficult and often beyond the expected efficacy. Rehabilita