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Quantitative analysis of asymmetric gene expression in the left-right organizer in response to flow forces: what comes downstream of cilia driven flow? – charon
Both motile and immotile cilia play important roles in left-right (LR) axis determination in several vertebrates. Establishment of the LR axis generally involves cilia-mediated directional flows in organized structures (LR organizers, LRO) in which the LR symmetry is broken, thus driving asymmetric