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Exploring the miPEP biology – biomiPEPs
miRNAs in plants, and analyse the conservation of their functions in phylogenetically distant plants. Because [...] into polypeptides. We have recently shown that in plants primary transcripts of miRNAs encode and direct [...] 2015, Nature). MiPEPs are produced naturally by plants and enhance specifically the expression of their
Viral deubiquitinases : new players in the control of plant virus infections – Viro-DUB
host/virus interactions in plants, thus opening new perspectives for plant protection against viruses [...] deubiquitinases : new players in the control of plant virus infections" aims at the elucidation of novel [...] control of viral infection. With a combination of plant molecular and cellular biology, biochemistry, functional
Plant systemic responses to changing root environments – PSYCHE
nitrogen-fixing plants in agro-ecological practices. Integrative developmental strategies allow plants to adapt [...] Plants, as sessile organisms, are highly impacted by environmental conditions. The soil is a highly [...] heterogeneous environment for plant nutrition composed of a mosaic of local favorable versus stressful
Type 3 secretion system for nitrogen-fixing symbiosis – SymEffectors
specialists in plant symbiosis and pathogenesis, will combine omics, bacterial and plant genetic approaches [...] signal to trigger the nodulation program of the host plant. For a long time, this key signal was assumed to [...] T3SS machinery, initially identified in animal and plant pathogens, permits the delivery of effector molecules
Deciphering the molecular mechanisms of sulfur trafficking in plants – SULTRAF
Sulfur represents an essential element for plant growth and development. As a major sulfur donor molecule [...] complex processes that are yet poorly described in plants. Among the processes requiring sulfur are the reactions [...] nucleophilic acceptors. Despite its importance for plant physiology, the molecular mechanisms of sulfur
Replaying the evolution of rhizobia: towards a conceptual and practical framework for the design of new nitrogen-fixing plant symbionts. – REPLAY
The tremendous role of microbiome in plant health and productivity is increasingly recognized, and has [...] t environmental services that microbes play to plants is biological nitrogen fixation i. e. the capacity [...] atmospheric nitrogen in a reduced form utilizable by plants. During evolution thousands of species in a few
Plant resistance to viruses induced by CytoRP, an RNase P-derived protein – CytoRP
The CytoRP project is based on the use of PRORP proteins, a novel family of plant RNase P enzymes involved in the maturation of tRNA precursors. These enzymes can, not only recognize and cut tRNAs, but also tRNA-like structures (TLS), such as the ones harboured at the 3’ end of the viral genome of many plant viruses. As such structures are essential for viral infectivity, their cleavage by PRORP is expected to prevent viruses from replicating and therefore would protect plants from infection.
Host factors involved in potyvirus cell-to-cell movement: new sources of resistance? – PotyMove
The overall objective of the PotyMove project is to identify plant factors involved in the cell-to-cell movement of the potyvirus genus, one of the largest group among plant viruses, causing considerable economic damage in crops worldwide. The aim of the proposal is to identify plant factors associated with a loss-of-susceptibility that can be used as resistance genes with higher durability, and be available to breeders for further transfer to crops
Cross-kingdom analysis of macrophage migration inhibitory factor (MIF) functions – X-KINGDOM-MIF
human and plant disease and have performed comprehensive in silico characterization of plant MIFs. In [...] study the molecular links between MIF of human, plant and parasite (aphid) origin to identify potentially [...] well as long-standing expertise in comparative plant immunity and molecular genetics of Arabidopsis thaliana
Aptamer-based peptide interference with type III effectors for broad-spectrum and durable resistance of crop plants – PAPTiCROPs
Bacterial plant pathogens are among the major constraints for stable food production. Many of them depend on the activity of a Type III Secretion System, which injects bacterial Type III Effector proteins (T3Es) into the host’s plant cells to the benefit of the pathogen. In this project, we propose to disarm bacterial phytopathogens by inhibiting the activity of conserved, key T3Es..