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Pathophysiological mechanisms of androgen and glucocorticoid receptors in skeletal muscle, and identification of new drug targets for prevention and treatment of muscle atrophy. – Androgluco
the identified AR and GR targets in muscle that control muscle mass and/or strength will be potential [...] Skeletal muscle is a dynamic tissue that has the capacity to regulate its size and function in response [...] response to a variety of external clues. Muscle inactivity, fasting, diseases (e.g. AIDS, cancers, septic
Musculoskeletal Individualized Multi-scale Environment – MIME
each muscle–tendon to line segments, with neither curved shape nor interaction between muscles due to [...] descriptions and muscle line-segment will be used in inverse dynamics and then to compute muscle forces (task [...] to volume modification. Volume muscle representation is one of the future major challenges in computer
Muscle and tendon interactions during development: Growth factors, transcription factors and collagens – Muscolten
This project aims at understanding the development of the musculo-skeletal system, by focusing on the interaction between muscles and tendons using adapted animal models.
ARMS : a multi arms robotic system for muscle separation – ARMS
through two operational scenarios: muscle/muscle separation and muscle bone separation. The consortium [...] project is to study the robotization of bovine muscle and bone separation in meat cutting and transformation [...] (such as knee-joints) and deformable (such as meat muscles). Leading edge technologies, such as smart sensors
Olive oil polyphenols, vitamin D and DHA synergistic effects on locomotor function – pOLIVd3
science-based dietary strategies to prevent bone and muscle loss (and to reduce fat mass), deals with issues [...] the human complexity at the physiological (bone, muscle, adipose tissue), metabolic (low grade inflammation [...] understanding of the influence of nutrition on bone and muscle health has mainly focused on calcium and proteins
Epithelial stem cell fate and epigenetic reprogramming – EPIStem
early developmental regulators of the skeletal muscle lineage. We subsequently demonstrated that PW1 [...] identify and purify stem cells from postnatal skeletal muscle, but serve to identify stem cells in many other [...] this analysis is being carried out in skeletal muscle (and funding is not requested here for this project)
Les obligations de confidentialités inhérentes au partenariat avec la société Babolat rendent difficiles l'expertise par des personnes étrangères, susceptibles de collaborer avec des concurrents de la société Babolat. – ACE
In tennis activity, the shoulder complex funnels the kinetic energy from the lower limbs and trunk to the upper limb and then the ball. The shoulder joint is characterized by large multidirectional ranges of motion. As a consequence, powerful, valid and reliable methods must be developed to describe the kinematics of tennis strokes, quantify the musculoskeletal loadings, and then establish the relationships between the racket characteristics, and muscle and joint stress.
Improving renutrition efficiency in elderly malnourished people for a better ageing. – PRESAGE
Undernutrition result in loss of mass mass in the older population and decline in muscle strength and mobility. The aim of the PRASEG study is to assess the impact of a specific renurtrion adapted to older poeple on nutritional statut and physical performances
Effects of chronic exposure of Airways to house Dust mite on bronchial asthmatic smooth muscle Mitochondria – AirDustMito
to house dust mite (HDM) on the bronchial smooth muscle (BSM) remodelling observed in asthma and particularly
TASK K+ channel contribution in central respiratory chemosensitivity – RESPITASK
Breathing adaptation to blood gas changes needs chemical sensors. Their molecular identity is not yet solved. Potassium channels of the TASK family, which are pH and oxygen sensitive, and which are localized in specific neurons are good candidates. They will be evaluated using genetically modified mice.