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Umbilical cord-derived mesenchymal stromal cells therapy in SARS-CoV-2-related ARDS – STROMA-CoV2
no treatment. Mesenchymal stem cells (MSC) feature several attractive characteristics: ease of procurement
Triangulenium as robust organic dyes for production of solar fuels – TATADyes
aza/seleno-triangulenium platforms will exhibit key features for photo-induced catalysis, never combined in
Tracking the evolution of human craniodental structures – GenoMorph
Recent advances in comparative cranial and dental structural morphology of extinct and extant hominins demonstrated that valuable (paleo)biological information can be extracted from their mineralized tissues for assessing taxonomy, evolutionary pathways and phylogenetic relationships. Substantial genetic component likely explains the variation of many of their morphological features. However, the genomic architecture of craniodental structures remains vastly unknown in humans.
Toward PrecisiOn Medicine for the Prediction of Treatment response in major depressive disorder through stratification of combined clinical and -omics signatures – PROMPT
(TRD). TRD is associated with specific clinical features and genetic/gene expression signatures. To date
Tiny, PrivAte, Proved & isolaTed – TinyPART
for privacy-by-design and cybersecurity. The key features of the TinyPART platform include mechanisms for
Thermodynamic investigations of mesoscopic 2D systems – THERMES-2D
s (skyrmions), specific temperature-dependent features at the various phase boundaries, and the existence
The effect of oxytocin on primate social behavior: a combined ultra-high-resolution fMRI and focused ultrasound study in macaques – FUSOT
Social dysfunction is a defining feature of many psychiatric and neurodevelopmental disorders, yet effective treatments are lacking. Oxytocin (OT) is a promising treatment. The ability of OT to cross the blood–brain barrier (BBB), however, is very limited. In addition, little is known about OT related social cognition circuits in primates due to the lack of site-specific OT administration tools.
Targeting neuromelanin-linked neuronal dysfunction and degeneration in ageing and Parkinson’s disease using a combined imaging and brain stimulation approach – NIPARK
trigger neurodegeneration which replicates many features of PD. By taking advantage of this newly developed
TOWARDS A MATERIALS DESIGN PLATFORM AIMED AT BIOELECTRONICS APPLICATIONS – MAPLLE
linking mixed-conduction properties with structural features in the molecular to the macroscopic scale.
Synthesis of Fluorinated Ni(IV) Organometallics. – Ni4Rf
Organofluorine compounds are ubiquitous in medicinal chemistry and agrochemistry. However, the creation of C-CF3 bonds mediated by metals is very challenging due to the M-CF3 bond strength. An original strategy to enable an easier reductive elimination of aryl-CF3 derivatives from well-defined aryl-M-CF3 platforms resides in the preparation of high oxidation state organometallics, more prone to be reduced by 2 electrons. The Ni4Rf project seeks to explore this strategy using Ni(III) and Ni(IV).