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Inhibitors of Chemokine receptors as Anti-inflammatory Reagents in the Eye – I-CKAIRE
Iinflammation is now considered as an important feature in many pathological conditions. Among immune mediators, chemokines control leukocyte trafficking. Chemokines and their receptors are thus central to the inflammatory process and are attractive targets for the pharmaceutical industry.
Investigating the roles of cilia during mammalian neurogenesis – CiliaStem
Ciliopathies are human pathologies characterized by ciliary deficiency and whose major clinical features include brain defects. We are focusing our efforts to decipher the molecular mechanisms involved in these pathologies by studying mouse genetic models.
Parsing and synthesis with abstract categorial grammars : from lexicon to discourse – Polymnie
Abstract Categorial Grammars (ACG). One of the features of this framework is to consider surface forms [...] improving a software the implements ACG related features. Together with the developed linguistic resources
Regulation of genome stability during embryonic development – checdev
The aim of this project is to understand how early embryos tolerate DNA damage and what are the consequences on genome stability
Build-up of Action Representation during Neurodevelopment: dysfunctions in Autism Spectrum Disorders? – ASD-BARN
debilitating developmental syndromes which core feature is social and communications disorders. Motor skill [...] to dyspraxia, or if they present with specific features. This project aims at deciphering the origin of
Constraint Event-Driven Automated Reasoning – CEDAR
The two main challenges for the coming to pass of the Semantic Web are (1) scalability and (2) distribution. The problem of scalability is that a well-designed web-oriented Knowledge Base (KB) system must be able to handle larger and larger volumes of knowledge without unbearable degradation of performance. Dealing with the second challenge (distribution) is as complex an issue since it must deal efficiently and seamlessly with knowledge spread all over the net under “real-life” conditions.
Innovative antimicrobial Agents based on Foldamers for the control of infection by pathogens of the biological Risk : Application to Bacillus anthracis – NEOTHERAPEUTICS
& Huc, Chem. Commun, 2011). Foldamers combine features that make them good candidates to target biom [...] whether these oligomers are endowed with necessary features such as favourable pharmacokinetics and activities
Anion Blended Materials Conception – ANION-CO
between anions will be applied to achieve specific features and properties. This project will be developed [...] of this family with the aim to exacerbate these features for potential applications as electrodes. - Nitrogen
Intelligent Retina for Innovative Sensing – IRIS
toward the implementation of fast and smart retina featuring a high fill factor, low power consumption, high [...] specifications of a new vision chip with unique features in terms of size, programmability and computational