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Developing a Social and Epistemological History of Psychiatric Epidemiology through a Case Study (Senegal) and international network – SEHPE
Psychiatric epidemiology remains unstudied as a historical and anthropological object, because of its: (1) late consolidation compared to other epidemiology fields; (2) problematic object – mental illness, mental health – which, in the absence of biomarkers, is relatively refractory to objectification and standardization; (3) highly variable social usages due to conceptual instability and contextual differences (global income disparities, postcolonial histories, public health cultures...).
JOKe and Empathy of a Robot/ECA: Towards social and affective relations with a robot – JOKER
will build and develop JOKER, a generic intelligent user interface providing a multimodal dialogue system [...] order to provide a companion-machine (robot or ECA) with the skills to create and maintain a long term social [...] content), a social interaction module modelling user and context, with long-term memories, and a generation
Candidate genes and pathways related to Autoimmune lymphoproliferative syndrome in a novel mouse strain deficient for Fas and P2X7 receptors – P2X7RFAS
produced, in collaboration with his french partner, a novel strain of C57Bl/6 (B6) mice bearing the lpr [...] On B6 genetic background, the lpr mutation induces a mild lymphoproliferation with limited autoimmune responses [...] responses. In contrast, MRL/lpr mice develop a systemic autoimmune disease resembling systemic lupus
Medication of a new concept on depression – MEDINCOD
effective use of a new type of AD embedded in a new concept to deliver the active molecule for a chronic treatment [...] is to validate a method to deliver the peptide for a several weeks treatment using a Medingel biopolymer [...] project is the development of a new treatment for depression. Depression is a disease particularly frequent
Gla-domainless Factor Xa as a new treatment of hemorrhages – MINITEN
Hemophilia is caused by a deficiency in factor VIII or IX. It is treated by the infusions of substitution products that cause the appearence of inhibitory antibodies in up to 30% of the cases. This limitation gave an oppportunity to developp alternative therapies.<br />Direct oral anticoagulants (DOA) target factor X and are used without antidotes. This creates threatened situations particularly in case of trauma-induced bleeds.
Prerequisite for therapeutic management of sequels from AbdomiNo-pelvic radioTHrapy by local injection of MSC combined with a hydrOgel and an HS-mimetic – ANTHOS
this construction in vivo in a model of severe colorectal ulceration and in a model of colonic anastomosis [...] which can be very incapacitating. Surgeons now have a therapeutic armamentarium to relieve symptoms, but [...] (army blood transfusion centre) have been developing a new treatment strategy using cell therapy and Mesenchymal
A study of job quality for cleaning occupations – CLEAN
lead to a rising isolation of this part of the labor force. At the same time, the development of a new branch [...] researchers involved in the project. A survey will be conducted on a sample of persons employed in four [...] the last ten years. These occupations represent now a high potential for employment and by now, account
Detection and identification of individual biomolecules translocating through a carbon nanotube – Nanophoresis
single biomolecules represents a path-breaking technology because it represents a label-free and amplification-free [...] to acceptable values. However, it is unlikely that a single type of nanopore will fulfil the requirements [...] applications. Actually, synthetic nanochannels having a versatile and perfectly-defined atomic structure do
Tomographic Atom Probe and Optical specTroscopy: a couplEd appRoach – TAPOTER
between a fs laser pulse and a nanometric object placed inside a strong electric field (i.e. a field emission [...] “evaporation”) of the atoms of a tip with a nanometric apex radius, immerged in a high electric field. In the [...] process is triggered by a femtosecond laser pulse. The evaporated ions are detected by a position- and tim
Crystal Nucleation On a Chip – CNOC
In this project, we are aiming for a real breakthrough in our understanding of the crystallization process by looking at the nucleation kinetics, through the combination of modern experimental techniques (microfluidics), Small Angle X-Ray Scattering (SAXS) from a synchrotron source and a new and original Monte Carlo simulation back and forth until we hopefully set up a clear understanding of the nucleation process.