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Mitochondrial transport mechanism at the molecular level – MIT-2M
Mitochondria are cellular organelles responsible for the production of ATP, the chemical fuel of the cell. Several metabolic cycles occur within this compartment. The function of this organelle necessitates the exchange of several types of metabolites and small molecules between the mitochondrial matrix and the cytoplasm. The project aims at understanding the transport mechanisms at a molecular level, more specifically the role of essential membrane proteins, the mitochondrial carriers.
Towards coherent radiation produced by particule beam accelerators injected with external lasers – DYNACO
systems, a strategy for producing coherent radiation consists of injecting external laser pulses on a relativistic [...] explore in a systematic way these strategies of creating coherent radiation, in the framework of a PhLAM-SOLEIL [...] emission. Recently, such strategies have revealed a very promising potential, in both extremes of the
Application of PICh for the characterization of the RNA Polymerase III transcription regulome – PIChClassIII
To exhaustively characterize RNA polymerase III regulators, one of the major process involved in the control of cell growth, we would like to set up a technique that will allow to purify 5S ribosomal DNA with its associated proteins.
CXC chemokines in neovascular eye disease – CHEMO-NED
there is a need of cheaper and more efficient treatments for these conditions. We are proposing a project [...] property protection through a number of patents. In the course of the project, a start-up should be set–up [...] has led to impressive results in clinical trials in a variety of human cancers. Most anti-angiogenesis
Contactless inspection of tubular inner surfaces – InSITUbes
structures, whose internal diameters can get up to a few tenths of millimeters. The return needs (in [...] of the roughness of these tubular structures is a normative requirement in many areas. However, inspection [...] use. This project proposes the development of a pre-industrial contactless demonstrator for inspection
Implementabilty and Robustness of Timed Systems – ImpRo
Implementability and Robustness of Timed Systems
Livestock and Local Development interactions and the ecological intensification – MOUVE
MOUVE is is a research consortium integrated by INRA, CIRAD and Cemagref researchers in partnership [...] to the pluridisciplinary of the project. From a methodological point of view, MOUVE will develop [...] The contrasts rely on i) landscape (rangeland or a mix with crops and forest); ii) livestock production
"Bivalent Chromatin and cell fate determination" – BIVANDEV
Pluripotent stem cells can differentiate in all cell types of an organism. During this process they progressively develop a narrower potential that results in commitment to specific cell fate with specific gene expression profile and functional property. Understanding how this process is regulated is of main importance both on fundamental and medical aspects. This is the objective of our project that focuses on a newly characterized actor believed to play a key role in cell fate determination.
-Genetic Diversity and Phenotypic Monotony in non-atherothrombotic arterial pathologies - 2 – GDPM-2
we propose to create a mouse model KI for MYH11, i.e. secondary to an anomaly in a contractile protein) [...] primary cultures of aortic cells, provide us with a unique opportunity to progress further in the pathology [...] studies, mainly focused on monogenic forms(13)and on a possible direct relationship between gene mutations
3D Comfort and Acceptance – 3D_COMFORT&ACCEPTANCE
3D is becoming a real challenge in the futur of digital entertainment. The 3D digital cinema market is [...] video games are going to be two other major market in a near future. The James Cameron's Movie has been the [...] Jacques Perrin). Creating 3D content will be soon a tremendous bussiness. The 3D content creation has