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Physics-Informed AI for Observation-driven Ocean AnalytiX – OceaniX
total budget amounts to 4M€, which the requested ANR grant covers 15%. Keywords: upper ocean dynamics
NEOnatal PREcursors of NEurodevelopment – NEOPRENE
For effective therapy of neurodevelopmental disorders, neonatal screening is necessary. The NEOPRENE project proposes that tactile perception and attention are the first foundations of cognitive development and that atypical touch processing at birth exerts a pervasive detrimental influence leading to syndrome-relevant, not syndrome-specific, impairments.
In situ delivery of Interleukin-7 to adjuvant mucosal vaccines – VacMucIL7
We demonstrated that Interleukine-7 (IL-7) is produced in infected mucosae and is able to trigger local expression of chemokines when administered either locally or systemically, leading to massive immune cell homing into targeted mucosae. We hypothesize that locally delivered IL-7 may act as an efficient adjuvant to trigger mucosal immune responses to vaccines.
Bridging dynamic and thermOdynamical REsponse of snowstorms to Anthropogenic forcing using Statistical mechanics – BOREAS
snowstorms.” Based on these improvements, I request the ANR-Tremplin the funding to start the analysis of large
Promote Open Science within the DRIIHM Interdisciplinary Research Facility on Human-Environment Interactions: Co-design of an e-infrastructure implementing the FAIR Principles – SO-DRIIHM
Human-Environment Interactions supported by the ANR (LabEx DRIIHM 2012-2025). This network involves nearly
Matilda: a bibliographic & bibliometric tool for open science – MATILDA
This project is therefore at the heart of the ANR's "Open Data" call for tenders, taking into account
Bs -> mu mu gamma: novel measurement and litmus test of flavour anomalies – GammaRare
We propose to use the measurement of the rare, radiative decay Bs0 ? µ+µ-? -- in particular the «indirect« measurement, i.e. without detection of the photon -- as a strategy to tell apart two alternative explanations of the so-called anomalies in the semi-leptonic decays of B mesons. One explanation is in terms of underestimated systematic uncertainties; the other one is in terms of genuine new physics.
Impact of the aberrant cell-matrix interaction in Non-Alcoholic fatty liver diseases progression – MATRIXNASH
Non-Alcoholic fatty liver diseases (NAFLD) with a 25% worldwide prevalence are leading causes of liver-related morbidity and mortality. Chronic inflammation (NASH) and associated fibrosis are the progressive forms of NAFLD and no pharmacological treatment is yet available. We will investigate how the extracellular matrix and its receptors play a key role in orchestrating chronic inflammation and fibrosis contributing to NAFLD progression.
Human DNA replication origins: reconciling disparate views – HUDROR
determinants of replication initiation. During previous ANR projects, we created novel methods to map replication
Synthesis and applications of planar chiral photoredox catalysts based on a [2.2]paracyclophane scaffold – PhotoChiraPhane
PhD student, who will be hired with the requested ANR grant. Three master students working for short-term