CE37 - Neurosciences intégratives et cognitives

The cerebellum in emotional learning – CerebellEMO

Submission summary

The cerebellum (Cb) is a major brain structure with extensive connections to both caudal brainstem and rostral sub-cortical areas. The Cb is eminently known for its control of motor functions. However recent findings suggest that it could also play a central role in the regulation of emotional behaviors via its interactions with limbic structures like the amygdala. Our hypothesis is that the Cb regulates affective states by computing and adjusting the coherence between external conditioning stimuli experienced and the ensuing emotional responses. Focusing on the processing of fear information, we will examine the affective implications of cerebellar activity by: 1) studying the fear prediction error signals generated by the Cb during emotional learning, 2) establishing the neural pathways that anatomically and functionally link the Cb with the amygdala, 3) examining the synaptic mechanisms that underlie the development of fear memories in cerebello-limbic circuits.

Project coordination

Daniela Popa (Institut de biologie de l'Ecole Normale Supérieure)

The author of this summary is the project coordinator, who is responsible for the content of this summary. The ANR declines any responsibility as for its contents.


NPS Neurosciences Paris-Seine
IBENS Institut de biologie de l'Ecole Normale Supérieure

Help of the ANR 295,158 euros
Beginning and duration of the scientific project: February 2022 - 48 Months

Useful links

Explorez notre base de projets financés



ANR makes available its datasets on funded projects, click here to find more.

Sign up for the latest news:
Subscribe to our newsletter