Ecologic historic and environnemental influence in Crohn Disease – CROPS

The cause of Crohn's disease (CD) is unknown and there is no cure. The ambition of this project is to contribute to understanding the cause. We will investigate whether the presence of pollutants in the external environment is a risk factor for CD. Is there a link between environmental quality (air, water and soil) and MC space clusters? Is there a difference in contamination between high and low incidence clusters of CD? Is the environment more degraded in high-impact clusters? If so, what pollutants cause these differences? The influence of social inequalities will be integrated into the interpretation of the results. We will diagnose each high/low incidence spatial cluster and then investigate the link with disease incidence within the clusters to determine if pollutants can be risk factors. A transdisciplinary consortium is the major asset of the project.