Multifunctional Bioactive and Magnetic Glass Nanoparticles for Bone Tissue Regeneration – Nano-BioMag

Because half of cancerous people develop secondary bone tumors (metastases), it is of tremendous importance to design new materials which will lead both to cancer cells destruction and fast bone tissue regeneration. This project aims to combine the high bioactivity property of nanometric bioactive glass particles synthesized by sol-gel chemistry to the magnetic properties of iron oxide nanoparticles through the synthesis of heterostructures. These magnetic particles would bring not only the possibility to realize hyperthermia treatment (heat generation under alternating magnetic field) in order to selectively destroy cancer cells, but also would have a positive impact on heterostructures bioactivity and bactericidity. The relationships between their structural, morphological, magnetic and biological (cytocompatibility, bioactivity, bactericidity) properties will be evaluated.