Développement, Epigénèse, Epigénétique et potentiel de vie

The LabEx DEEP aims to decipher the complexity of life and development of a whole organism, from the germ line and stems cells up to the transitions between normal and disease states. It comprises 14 research teams affiliated to the Institut Curie UMR3215/U934 and UMR3664. Coordinated by E. Heard and G. Almouzni from 2012 to 2018, it is, since 2019, coordinated by G. Almouzni–senior team leader UMR3664– and P. Le´opold–unit director UMR3512/U934.

In 2020, DEEP strategic actions involved launching a call for a junior group in UMR3664, and the development of 4 cutting-edge technological platforms. It also promoted connections between LabEx teams within the PSL ecosystem, and contributed to key (inter)national initiatives. The interaction with our Scientific Advisory Board, the co-organization of the international meeting of the Epigene2Sys network and participation, in the Coordination Support Action for the LifeTime initiative fostered our excellence and international visibility.

While the pandemic affected our training and outreach activities at first, we rapidly adapted to online formats for all actions: courses co-organized, international conferences, career development and outreach projects.

Finally, DEEP encouraged innovation by providing logistical support and seeding fundings for technology transfer projects. It supported a successfully funded 2020 SESAME application enabling the acquisition of a PALM/STORM microscope and high-pressure freezer for the development of CLEM methods at PSL and launched a “single-cell” call for young researchers.

Overall, DEEP boosted the dynamics of all our activities as highlighted by outstanding scientific achievements and impact in innovation.