Projets financés

Sleep-wake disturbances (SWD) such as sleep fragmentation and excessive daytime sleepiness are early symptomatic manifestations of prodromal Parkinson’s disease (PD) and occur in up to 90% of patients over the course of the disease. They are a major source of PD-related disability, diminished qualit

Focused ultrasound (FUS) is a non-invasive, ground-breaking technique suggested for the treatment of Alzheimer’s disease (AD). The partners of the REBALANCE consortia have demonstrated therapeutic efficacy for FUS alone and FUS stimulation combined with microbubbles. At the cellular level, FUS promo

High-fat nutritional supplementation is the first non-pharmacological treatment recognized in clinical trials to significantly prolong the survival of a large fraction of ALS patients, in particular the fast progressors. Here we hypothesize that the efficacy of the high-fat diet is linked to central

Aerobic exercise or cognitive training, as well as the combination of both (referred to as environmental enrichment, EE) can enhance synaptic plasticity, improve memory function and ameliorate disease phenotypes in animal model for age-associated neurodegenerative diseases, such as Alzheimer’s disea

Trans-spinal direct current stimulation (tsDCS) is a modern non-invasive neuromodulation technique with a unique capability of providing non-pharmacological, safe and cost-efficient treatment in several neurodegenerative conditions. The goal of the DC4MND consortium is to decipher the biophysical, e