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Coupling of Phenols and Indoles towards benzofuroindolines analogs of diazonamide A. – CouPhIn
Diazonamide A is a complex compound of marine origin, available in very small amount but presenting very promising anticancer activities. The goal is to synthezise «simplified diazonamides« still efficient against cancer cells via new chemical methods inspired by Nature.
Mathematical models of Local Adaptation – MOLA
Models of Local Adaptation” will explore different types of models of adaptation to heterogeneous environments [...] (CIRB, CNRS/UMR 7241 INSERM U1050) at the Collège de France in Paris
In the Deep, Dark Lyman-Alpha Forest: Exploring Dark Energy and Galaxy Formation Using the Intergalactic Medium – DEEPDARKFOREST
the next generation dark energy surveys of this type set to begin in late 2018. One is part of the Dark [...] Stars’) to join the host, Laboratoire d'Astrophysique de Marseille (LAM), in September 2014. Accepting this
Deciphering stress-induced immune alterations and their contribution to physiopathological mechanisms in Parkinson's disease. – ParkSTRIM
unknown. Our basic and simplified hypothesis is that de-regulated HPA axis may affect PD patients’ responses [...] Genetic-based i.e. viral-driven overexpression of wild type and mutated aSyn. Cell-specific GR functions will
Weak KAM beyond Hamilton-Jacobi – WKBHJ
y address are: large time behavior of curvature type flows, large time behavior in degenerate second [...] last project we had two good postdocs: one is Maître de Conférences in Nice the other is Assistant professor
Innovative theranostic approaches based on simultaneous drug release and in situ synthesis of fluorophores/photosensitizers – InnoTherano
glycosidases). This fluorogenic "covalent-assembly" type process will be accompanied by the concomitant release [...] NG-FTAs without resorting to tedious and time-consuming de novo syntheses. Our second objective will be to apply
Méthodes hamiltoniennes et markoviennes en mécanique quantique hors équilibre – HAM-MARK
the convergence of such systems are then of the type of those used for usual Markov processes (recur [...] the Lindblad semigroup (Attal-Pautrat, Derezinski-De Roeck). In some cases the two approaches match: a
Mountain huts as observatories of tourism transition. The repositioning of less-developed mountain areas and their related professions in the French-Swiss Alps – HutObsTour
previous programs: "Les refuges comme observatoires de la transition récréative en montagne" (seed funding [...] research. In order to cross-reference sources and types of data appropriate to the strong socio-geographical
Blood-brain barrier crossing of conventional and new antidotes to treat organophosphate poisoning. – BHE-OP-Antidotes
complementary and validated in vivo models for this type of work, the zebrafish larva and the mouse. These [...] Chapouly (Partner n ° 4, INSERM U1034, University de Bordeaux) (mouse model, in vitro and in vivo studies